OTTMUSG00000021028 Inhibitors
TTMUSG00000021028 Inhibitors refers to a chemical class designed to interact with a specific molecular target denoted by the identifier OTTMUSG00000021028. Such inhibitors are typically characterized by their ability to bind to and modulate the function of their target protein or enzyme, which is encoded by the gene associated with the OTTMUSG00000021028 identifier. The nature of this interaction is based on the structural complementarity between the inhibitor and the active or allosteric site of the protein. The precise molecular mechanisms by which these inhibitors exert their effect depend on the biological role of the target protein and the specific chemical structure of the inhibitor itself.
The development and characterization of OTTMUSG00000021028 Inhibitors involve extensive research into the molecular biology and biochemistry of the target, as well as the chemistry of the inhibitors. Scientists employ various techniques such as high-throughput screening, computational modeling, and structure-activity relationship (SAR) studies to identify and refine these chemical entities. These studies enable an understanding of how the inhibitors interact at an atomic level with the target site, which is critical for the optimization of their binding properties. The resulting inhibitors are often a product of iterative cycles of design, synthesis, and testing to achieve the desired level of specificity and potency in modulating the function of the target protein without affecting other biological processes.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent phosphoinositide 3-kinase (PI3K) inhibitor that can prevent the activation of AKT, downstream of PI3K signaling. If OTTMUSG00000021028 is part of the PI3K/AKT pathway, Wortmannin would result in its inhibition by blocking the pathway upstream. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that impedes the mTORC1 pathway. If OTTMUSG00000021028 is regulated by mTOR signaling, Rapamycin would inhibit its function by preventing pathway activation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor which would block p38 MAPK activation. If OTTMUSG00000021028's function is dependent on p38 MAPK signaling, its activity would be decreased by SB203580. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A MEK inhibitor that could disrupt the ERK/MAPK pathway. If OTTMUSG00000021028 is involved in this pathway, PD98059 would indirectly inhibit its activity by blocking MEK, which is upstream in the pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor similar to Wortmannin, which would also inhibit the PI3K/AKT pathway and could reduce the activity of OTTMUSG00000021028 if it is involved in this pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Another MEK inhibitor that would inhibit the ERK/MAPK pathway. If OTTMUSG00000021028 is a downstream effector in this pathway, U0126 would decrease its activity by impeding pathway activation upstream. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of the JNK pathway, which would prevent JNK signaling. If OTTMUSG00000021028 is activated by JNK signaling, SP600125 would inhibit the protein's activity. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
An Aurora kinase inhibitor that could affect cell cycle progression. If OTTMUSG00000021028 is involved in cell cycle regulation via Aurora kinases, its activity would be inhibited by ZM-447439. | ||||||
Saracatinib | 379231-04-6 | sc-364607 sc-364607A | 10 mg 200 mg | $113.00 $1035.00 | 7 | |
A Src family kinase inhibitor which would interfere with signaling pathways involving Src kinases. If OTTMUSG00000021028 is activated by Src kinase signaling, AZD0530 would inhibit its functional activity. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that could lead to the accumulation of regulatory proteins and potentially inhibit OTTMUSG00000021028 if it is regulated by proteasomal degradation. | ||||||