Arylacetamide deacetylase-like 4-like, also known as Gm13124, plays a crucial role in cellular processes through its enzymatic activity. This protein is involved in various cellular pathways, including those related to gene expression regulation and metabolic control. Its activation is essential for maintaining cellular homeostasis and functionality. The general mechanisms of activation of Arylacetamide deacetylase-like 4-like involve the modulation of specific signaling pathways and cellular processes. Several chemicals have been identified as activators of this protein. Resveratrol, for example, activates Arylacetamide deacetylase-like 4-like by modulating the Sirtuin pathway, leading to the deacetylation of proteins and subsequent activation. Curcumin inhibits NF-κB signaling, indirectly upregulating the target protein's activity. Forskolin elevates cAMP levels, activating protein kinase A (PKA), which in turn activates Arylacetamide deacetylase-like 4-like.
Other chemicals, such as Epigallocatechin gallate (EGCG), 3,3'-Diindolylmethane (DIM), Quercetin, Berberine, Genistein, N-Acetylcysteine (NAC), Sodium butyrate, Ginsenoside Rg1, and Alpha-lipoic acid, also contribute to the activation of Arylacetamide deacetylase-like 4-like through various mechanisms. These chemicals target specific pathways and cellular processes, ultimately leading to the functional activation of the protein. In summary, Arylacetamide deacetylase-like 4-like is a vital protein involved in various cellular processes, and its activation is achieved through the modulation of specific pathways and cellular mechanisms by a range of chemical activators. These chemicals play a crucial role in maintaining the functionality of Arylacetamide deacetylase-like 4-like, making it an important player in cellular homeostasis and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is known to activate Arylacetamide deacetylase-like 4-like by modulating the Sirtuin pathway. It promotes deacetylation of proteins, leading to the activation of the target protein. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin activates Arylacetamide deacetylase-like 4-like by inhibiting NF-κB signaling, which indirectly upregulates the target protein's activity. It also has antioxidant properties. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG activates Arylacetamide deacetylase-like 4-like by inhibiting histone deacetylases (HDACs), leading to increased acetylation of proteins involved in its pathway. | ||||||
3,3′-Diindolylmethane | 1968-05-4 | sc-204624 sc-204624A sc-204624B sc-204624C sc-204624D sc-204624E | 100 mg 500 mg 5 g 10 g 50 g 1 g | $37.00 $65.00 $89.00 $421.00 $681.00 $66.00 | 8 | |
DIM activates Arylacetamide deacetylase-like 4-like by modulating the aryl hydrocarbon receptor (AhR) pathway. It enhances AhR-mediated gene expression, indirectly activating the target protein. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin activates Arylacetamide deacetylase-like 4-like by inhibiting the PI3K/Akt pathway, which leads to the activation of FOXO transcription factors that regulate the target protein. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates Arylacetamide deacetylase-like 4-like by promoting AMP-activated protein kinase (AMPK) activation, which subsequently upregulates the target protein's activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein activates Arylacetamide deacetylase-like 4-like through the inhibition of tyrosine kinases, particularly the epidermal growth factor receptor (EGFR) pathway. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
NAC activates Arylacetamide deacetylase-like 4-like by replenishing intracellular glutathione levels, which helps maintain the protein's redox status and functional activation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate activates Arylacetamide deacetylase-like 4-like by inhibiting histone deacetylases (HDACs), leading to increased acetylation of proteins involved in its pathway. | ||||||
Ginsenoside Rg1 | 22427-39-0 | sc-205708 sc-205708A | 5 mg 10 mg | $265.00 $486.00 | ||
Ginsenoside Rg1 activates Arylacetamide deacetylase-like 4-like by enhancing nitric oxide (NO) production, which influences signaling pathways that indirectly activate the target protein. | ||||||