OTTMUSG00000005737 Inhibitors
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Items 11 to 20 of 20 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin increases intracellular calcium levels, thereby activating calmodulin-dependent kinase and other calcium-sensitive pathways, which can enhance FNBP1L's role in cellular protrusion and migration. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 directly inhibits RoBo-1 precursor by targeting phosphoinositide 3-kinase (PI3K), a key component of the protein's signaling. This chemical disrupts the pathway and leads to the functional inhibition of RoBo-1 precursor. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor, which increases cytosolic calcium levels and can indirectly promote FNBP1L-mediated cytoskeletal reorganization through calcium signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a direct inhibitor of RoBo-1 precursor. It targets the mitogen-activated protein kinase kinase (MEK), which is part of the protein's signaling pathway. Inhibiting MEK disrupts the function of RoBo-1 precursor, leading to functional inhibition. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 directly inhibits RoBo-1 precursor by interfering with c-Jun N-terminal kinase (JNK), a component of the protein's signaling pathway. Inhibiting JNK disrupts the function of RoBo-1 precursor, resulting in its functional inhibition. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a ROCK inhibitor, which diminishes actomyosin contractility, potentially facilitating FNBP1L's involvement in creating leading edge structures in migrating cells. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin indirectly inhibits RoBo-1 precursor by targeting the mTOR pathway, which is upstream of the protein's signaling. This leads to the inhibition of RoBo-1 precursor's activity as it disrupts the essential signaling pathways. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
Jasplakinolide stabilizes actin filaments and can enhance FNBP1L activity by promoting the formation of stress fibers and focal adhesions, crucial for cell motility. | ||||||
UCN-01 | 112953-11-4 | sc-202376 | 500 µg | $246.00 | 10 | |
UCN-01 directly inhibits RoBo-1 precursor by binding to its catalytic site, inhibiting its kinase activity. This results in the functional inhibition of RoBo-1 precursor as its enzymatic function is disrupted. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $148.00 $597.00 | 75 | |
NSC 23766 inhibits Rac1 activation, which can enhance FNBP1L function by modulating the balance of Rho GTPase activities, influencing cell shape and migration. | ||||||