Date published: 2026-3-3

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OTTMUSG00000005737 Activators

Protein RoBo-1 precursor, encoded by the Gm12253 gene, represents a pivotal player in the intricate orchestra of cellular processes. This multifaceted protein, with its intricate functionality, holds a crucial role in various signaling pathways within the cell. Its primary function revolves around orchestrating responses to a range of extracellular cues and coordinating cellular activities in response to these signals. The precise functionality of Protein RoBo-1 precursor spans a spectrum of cellular processes, encompassing everything from cell growth and differentiation to immune response modulation. Within these realms, it plays a central role in fine-tuning cell responses to diverse stimuli, thereby contributing to the maintenance of cellular homeostasis. In essence, Protein RoBo-1 precursor can be likened to a conductor of a symphony, directing the cellular orchestra to harmoniously respond to its ever-changing environment.

The activation of Protein RoBo-1 precursor is achieved through a myriad of mechanisms, each with its unique approach to fine-tune the protein's activity. These mechanisms range from the elevation of intracellular cyclic adenosine monophosphate (cAMP) levels and the modulation of calcium concentrations to receptor-mediated signaling and the direct promotion of gene transcription. These intricate processes reflect the adaptability and versatility of Protein RoBo-1 precursor, allowing it to integrate and interpret a wide array of signals. In essence, its activation can be likened to a complex choreography involving various molecular partners and pathways, resulting in the orchestration of specific cellular responses. These mechanisms, while diverse, converge to enhance the functional activity of Protein RoBo-1 precursor, enabling it to fulfill its pivotal role in mediating cellular responses to a dynamic and ever-changing cellular environment.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid activates Gm12253 by binding to retinoic acid receptors (RARs) and promoting the transcription of Gm12253. This results in increased Gm12253 expression and functional activation in relevant cellular processes.

Sodium Orthovanadate

13721-39-6sc-3540
sc-3540B
sc-3540A
5 g
10 g
50 g
$49.00
$57.00
$187.00
142
(4)

Sodium orthovanadate activates Gm12253 by inhibiting protein tyrosine phosphatases (PTPs), leading to increased phosphorylation of Gm12253. Elevated phosphorylation enhances the functional activation of Gm12253.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates Gm12253 by stimulating protein kinase C (PKC). Activated PKC phosphorylates Gm12253, enhancing its activity. PMA-mediated PKC activation is crucial for the functional activation of Gm12253 in various cellular processes.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Thapsigargin activates Gm12253 by inhibiting the sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, leading to increased cytosolic calcium levels. Elevated calcium activates Gm12253 through calcium-dependent pathways.

2-APB

524-95-8sc-201487
sc-201487A
20 mg
100 mg
$28.00
$53.00
37
(1)

2-APB activates Gm12253 by modulating intracellular calcium levels. It inhibits inositol trisphosphate receptor (IP3R), leading to increased calcium release, which can activate Gm12253 through calcium-dependent signaling pathways.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Ionomycin activates Gm12253 by directly increasing intracellular calcium levels. Elevated calcium activates Gm12253 through calcium-dependent pathways, enhancing its functional activity in relevant cellular processes.

Thrombin from human plasma

9002-04-4sc-471713
100 U
$235.00
(0)

Thrombin activates Gm12253 through protease-activated receptors (PARs) signaling. PARs activation triggers intracellular signaling cascades, including Gm12253 phosphorylation, enhancing its functional activity in various cellular processes.

Phosphatidic Acid, Dipalmitoyl

169051-60-9sc-201057
sc-201057B
sc-201057A
100 mg
250 mg
500 mg
$106.00
$244.00
$417.00
(1)

Phosphatidic acid activates Gm12253 by directly binding and activating mTORC1, a key regulator of protein synthesis and cell growth. Activation of mTORC1 leads to increased Gm12253 translation and functional activation.