Date published: 2025-11-24

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OR4C13 Inhibitors

OR4C13 inhibitors represent a variety of compounds that, while not directly targeting OR4C13, affect it through different cellular mechanisms. The action of sodium azide and dinitrophenol on cellular respiration reduces the levels of ATP necessary for proteins like OR4C13 to maintain their functional conformation. As ATP is critical for many cellular functions, a decrease in its availability can have widespread effects, particularly on ATP-dependent proteins, potentially including OR4C13. The inhibition of PI3K by compounds like quercetin and LY294002 would result in reduced phosphorylation of proteins within the pathways that OR4C13 is involved in, potentially leading to a decrease in its activity. Staurosporine, with its broad kinase inhibition, could affect a range of phosphorylation events, some of which might be crucial for maintaining OR4C13 activity. In addition, rapamycin's inhibition of the mTOR pathway affects the synthesis of proteins, which could result in a decrease in proteins that regulate or interact with OR4C13, leading to diminished function. Similarly, the inhibition of DNA crosslinking by mitomycin C and the blockade of CDKs by alsterpaullone can lead to a reduced repertoire of cellular proteins, including those necessary for OR4C13 activity. Geldanamycin's destabilization of Hsp90 client proteins could directly impact OR4C13 if it is an Hsp90 client, or it could affect its function indirectly by destabilizing proteins that regulate OR4C13.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sodium azide

26628-22-8sc-208393
sc-208393B
sc-208393C
sc-208393D
sc-208393A
25 g
250 g
1 kg
2.5 kg
100 g
$42.00
$152.00
$385.00
$845.00
$88.00
8
(2)

Sodium azide disrupts ATP production by inhibiting mitochondrial cytochrome c oxidase. Since ATP is vital for the energy-dependent conformation of OR4C13, its inhibition can lead to conformational instability and reduced functional activity of OR4C13.

2,4-Dinitrophenol, wetted

51-28-5sc-238345
250 mg
$58.00
2
(1)

Dinitrophenol uncouples oxidative phosphorylation, impeding ATP synthesis. Insufficient ATP can cause a decrease in the conformational stability of OR4C13, which relies on ATP for proper function.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin inhibits PI3K, a kinase involved in signaling pathways that regulate protein synthesis and turnover. Inhibition of PI3K could reduce phosphorylation of proteins that interact with OR4C13, leading to its decreased functional activity.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 inhibits PI3K, reducing AKT signaling and phosphorylation of downstream proteins. If OR4C13's activity is regulated by proteins modulated by PI3K/AKT signaling, its activity would decrease as well.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine broadly inhibits kinases, affecting phosphorylation of proteins in signaling networks. A decrease in phosphorylation events within OR4C13's network could reduce its activity.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin inhibits mTOR, causing downregulation of protein synthesis. This can decrease the production of proteins that regulate OR4C13, leading to a reduction in its functional activity.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$65.00
$99.00
$140.00
85
(5)

Mitomycin C crosslinks DNA, inhibiting the cell cycle and reducing protein synthesis capacity. This could indirectly affect OR4C13's levels and function.

Alsterpaullone

237430-03-4sc-202453
sc-202453A
1 mg
5 mg
$67.00
$306.00
2
(1)

Alsterpaullone inhibits CDKs, impeding cell cycle progression and potentially decreasing turnover of proteins that regulate OR4C13, leading to its functional inhibition.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$38.00
$58.00
$102.00
$202.00
8
(1)

Geldanamycin inhibits Hsp90, destabilizing client proteins. If OR4C13 relies on Hsp90 for folding or function, or if it interacts with Hsp90 client proteins, its activity would be decreased.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

U0126 inhibits MEK, disrupting the MAPK pathway. If OR4C13's function is regulated by this pathway, its activity would be reduced following MEK inhibition.