OR2T5 Activators
The chemical class referred to as OR2T5 Activators encompasses a group of compounds known for their ability to modulate the activity of the OR2T5 gene. OR2T5, or Olfactory Receptor Family 2 Subfamily T Member 5, is a gene that belongs to the large family of olfactory receptor genes. These genes encode proteins that are expressed in the olfactory sensory neurons of the nasal epithelium and are responsible for detecting and transducing odorant signals. Activators of OR2T5 are substances capable of enhancing the expression or function of this gene, potentially influencing the sensitivity or responsiveness of olfactory neurons to specific odorants.
Characterizing compounds as OR2T5 Activators typically involves screening processes aimed at evaluating their ability to interact with regulatory elements of the OR2T5 gene or modulate the activity of proteins involved in olfactory signal transduction. These activators may act through various mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for OR2T5 gene expression, or modulating the function of proteins involved in odorant detection pathways. Understanding the molecular mechanisms underlying OR2T5 activation by these compounds is crucial for unraveling the complexities of olfactory perception and elucidating the roles of specific olfactory receptors in detecting environmental odors. Further research into OR2T5 Activators may provide insights into the diversity of odorant responses and olfactory receptor function, contributing to our understanding of olfactory processing and perception.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
As a second messenger in GPCR signaling, cAMP may upregulate OR2T5 expression by activating protein kinase A (PKA), which can lead to transcriptional activation of some olfactory receptor genes. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in differentiation and development, Retinoic Acid could influence OR2T5 expression by modulating gene expression patterns in olfactory receptor neurons during development or regeneration. | ||||||
Icilin | 36945-98-9 | sc-201557 sc-201557A | 10 mg 50 mg | $91.00 $257.00 | 9 | |
A cooling agent that activates certain transient receptor potential (TRP) channels, Icilin might indirectly affect OR2T5 expression by modulating sensory neuron activity and signaling pathways. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
Known for activating cold-sensitive TRP channels, Menthol could indirectly influence OR2T5 expression through its effects on sensory neuron signaling and potential feedback mechanisms on olfactory receptor gene expression. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc ions play a role in neurotransmission and neuronal function. Zinc Gluconate could hypothetically affect OR2T5 expression through its involvement in neuronal health and signaling pathways. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
A known activator of heat-sensitive TRP channels, Capsaicin could indirectly modulate OR2T5 expression by affecting sensory neuron activity and the signaling environment in the olfactory epithelium. | ||||||
Sodium Chloride | 7647-14-5 | sc-203274 sc-203274A sc-203274B sc-203274C | 500 g 2 kg 5 kg 10 kg | $19.00 $30.00 $60.00 $110.00 | 15 | |
High concentrations of Sodium Chloride can affect cellular osmolarity and signaling. It might influence OR2T5 expression indirectly through osmotic stress responses in olfactory receptor neurons. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
A compound found in citrus oils, Citral could potentially modulate OR2T5 expression by acting as a ligand for olfactory receptors, thereby influencing receptor expression through feedback mechanisms. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Found in clove oil, Eugenol might affect OR2T5 expression by serving as a ligand for olfactory receptors, potentially triggering regulatory mechanisms that adjust receptor expression. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Common in citrus peel oils, Limonene could hypothetically influence OR2T5 expression by acting as an odorant molecule, potentially affecting olfactory receptor gene regulation through olfactory signal transduction pathways. | ||||||