OR2T5 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(+)-Bicuculline | 485-49-4 | sc-202498 sc-202498A | 50 mg 250 mg | $80.00 $275.00 | ||
Bicuculline inhibits OR2T5 by blocking GABA_A receptors that indirectly influence olfactory receptor neurons' signal transduction. GABA_A receptor inhibition can alter the neuronal excitability and signal processing in the olfactory bulb, potentially inhibiting OR2T5 function. | ||||||
6-Cyano-7-nitroquinoxaline-2,3-dione | 115066-14-3 | sc-505104 | 10 mg | $204.00 | 2 | |
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits OR2T5 by blocking AMPA receptors that are part of the glutamatergic signaling involved in olfactory processing. By inhibiting these receptors, 6-Cyano-7-nitroquinoxaline-2,3-dione disrupts the glutamate-mediated excitatory signals, potentially leading to inhibition of OR2T5 activity. | ||||||
D(−)-2-Amino-5-phosphonovaleric acid (D-AP5) | 79055-68-8 | sc-200434 | 5 mg | $95.00 | 2 | |
D-AP5 inhibits OR2T5 by antagonizing NMDA receptors, which play a critical role in synaptic plasticity and neurotransmission in the olfactory bulb. NMDA receptor inhibition can reduce the excitatory signals, possibly inhibiting OR2T5 function. | ||||||
Niflumic acid | 4394-00-7 | sc-204820 | 5 g | $31.00 | 3 | |
Niflumic acid inhibits OR2T5 by blocking chloride channels, including those modulated by GABA and glycine receptors, which are involved in the olfactory system's signal transduction. This inhibition could disrupt the ionic balance necessary for OR2T5 activation. | ||||||
Lidocaine | 137-58-6 | sc-204056 sc-204056A | 50 mg 1 g | $50.00 $128.00 | ||
Lidocaine inhibits OR2T5 by blocking sodium channels on olfactory receptor neurons, preventing action potential initiation and propagation, which is essential for OR2T5 function. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $184.00 $245.00 | 13 | |
Ruthenium Red inhibits OR2T5 by blocking calcium channels involved in the olfactory signal pathway, preventing calcium influx essential for activation of signal transduction pathways, thus inhibiting OR2T5 function. | ||||||
Mibefradil dihydrochloride | 116666-63-8 | sc-204083 sc-204083A | 10 mg 50 mg | $209.00 $848.00 | 4 | |
Mibefradil inhibits OR2T5 by blocking T-type calcium channels, which are involved in the regulation of neuronal firing and signal transduction in olfactory neurons, potentially inhibiting OR2T5 activity. | ||||||
Capsazepine | 138977-28-3 | sc-201098 sc-201098A | 5 mg 25 mg | $145.00 $450.00 | 11 | |
Capsazepine inhibits OR2T5 by blocking TRPV1 channels, which may play a role in olfactory signal transduction by modulating ion flux and neuronal excitability, thereby potentially inhibiting OR2T5 function. | ||||||
SK&F 96365 | 130495-35-1 | sc-201475 sc-201475B sc-201475A sc-201475C | 5 mg 10 mg 25 mg 50 mg | $101.00 $155.00 $389.00 $643.00 | 2 | |
SK&F 96365 inhibits OR2T5 by blocking receptor-operated calcium channels, thereby inhibiting calcium influx essential for activating signal transduction pathways within olfactory neurons, leading to the inhibition of OR2T5 function. | ||||||