Olr374 inhibitors represent a specialized group of chemical compounds that target the Olfactory receptor 374 (Olr374), a protein encoded by the Olr374 gene. Olfactory receptors, such as Olr374, are G protein-coupled receptors (GPCRs) primarily involved in the detection of odor molecules, contributing to the sense of smell. The inhibition of Olr374 by these compounds generally occurs through competitive binding at the receptor's active site, preventing the receptor from interacting with its natural ligands. The molecular structure of Olr374 inhibitors often features unique functional groups that allow them to effectively bind to the receptor, thereby modulating its activity. This modulation can result in altered signal transduction pathways associated with olfactory perception, showcasing the significance of these inhibitors in the study of olfactory signaling mechanisms.
The study of Olr374 inhibitors is crucial for understanding the structural and functional dynamics of olfactory receptors. By investigating the binding affinity, selectivity, and specificity of these inhibitors, researchers can gain insights into the molecular underpinnings of olfactory receptor activation and deactivation. Furthermore, the chemical properties of Olr374 inhibitors, including their solubility, stability, and reactivity, play a pivotal role in determining their efficacy in receptor modulation. These inhibitors also provide valuable tools for dissecting the role of Olr374 in various physiological and biochemical processes, as well as for probing the broader family of olfactory receptors to which Olr374 belongs. The development and refinement of Olr374 inhibitors contribute to the expanding knowledge of GPCR function and regulation, offering a deeper understanding of the complex signaling networks that govern sensory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Proteasome inhibitor, potentially alters degradation of proteins involved in cell cycle regulation. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $111.00 $357.00 | 8 | |
Modulates immune response and angiogenesis, potentially affecting inflammatory and growth pathways. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $251.00 $500.00 $547.00 | 16 | |
JAK inhibitor, potentially disrupts signaling in inflammatory and hematopoietic pathways. | ||||||
Trametinib | 871700-17-3 | sc-364639 sc-364639A sc-364639B | 5 mg 10 mg 1 g | $114.00 $166.00 $947.00 | 19 | |
MEK inhibitor, potentially affects MAPK/ERK signaling in melanoma and other cancers. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $156.00 | 5 | |
BTK inhibitor, potentially alters B-cell receptor signaling in certain leukemias and lymphomas. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
CDK4/6 inhibitor, potentially affects cell cycle regulation in breast cancer. | ||||||
ABT-199 | 1257044-40-8 | sc-472284 sc-472284A sc-472284B sc-472284C sc-472284D | 1 mg 5 mg 10 mg 100 mg 3 g | $118.00 $337.00 $520.00 $832.00 $1632.00 | 10 | |
BCL-2 inhibitor, potentially induces apoptosis in chronic lymphocytic leukemia. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $153.00 $938.00 | 5 | |
Multi-targeted tyrosine kinase inhibitor, potentially disrupts angiogenesis and tumor cell proliferation. | ||||||