Olfr866 Activators
Olfr866 is a protein with a critical role in cellular processes and signal transduction pathways. Its function is pivotal in orchestrating specific responses within the cell, and understanding the mechanisms of its activation is of utmost importance. This protein serves as a key player in cellular signaling, facilitating the transmission of extracellular signals to intracellular events. Olfr866, while not directly involved in transcriptional regulation or gene expression, contributes significantly to the intricate web of molecular interactions within the cell. Activation of Olfr866 can occur through a variety of mechanisms. One common mode of activation involves the binding of specific chemicals to Olfr866's regulatory domains or allosteric sites. These interactions induce conformational changes in the protein, leading to its functional activation. Additionally, Olfr866 can be indirectly activated through the modulation of various upstream signaling components, such as G-protein coupled receptors (GPCRs) and kinases. These components form an interconnected network that converges on Olfr866, ultimately promoting its activation and participation in relevant cellular responses.
The general mechanisms of Olfr866 activation revolve around the regulation of downstream signaling pathways. Upon activation, Olfr866 becomes a critical node in these pathways, facilitating the transmission of signals from extracellular stimuli to intracellular events. This activation triggers a cascade of molecular events, often involving second messengers like cAMP or calcium ions, which further propagate the signal. While the specific pathways and cellular responses mediated by Olfr866 may vary, the overarching theme is its role in fine-tuning cellular processes and coordinating the cellular response to external cues. In conclusion, Olfr866 is a key player in cellular signaling, contributing to the intricate web of molecular interactions within the cell. Its activation mechanisms involve direct chemical binding and indirect modulation of upstream signaling components, all aimed at coordinating specific cellular responses. Understanding these activation processes is essential for unraveling the complexities of cell signaling and the role Olfr866 plays in cellular function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin is a direct activator of Olfr866, as it stimulates adenylate cyclase, leading to an increase in intracellular cAMP levels. This elevated cAMP activates Olfr866 through a protein kinase A (PKA)-dependent pathway, resulting in the protein's functional activation and involvement in downstream signaling cascades. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Isoproterenol is a beta-adrenergic agonist that directly activates Olfr866 by binding to beta-adrenergic receptors on the cell membrane. This binding initiates a signaling cascade involving cAMP and PKA, ultimately leading to the functional activation of Olfr866 and its participation in specific cellular responses and signal transduction pathways. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
8-Bromo-cAMP is a direct activator of Olfr866 that mimics the action of cAMP. It activates Olfr866 by binding to the protein's regulatory domain, inducing conformational changes that promote its functional activity. This activation triggers downstream signaling pathways, allowing Olfr866 to carry out its specific functions in cellular responses and signal transduction. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Phorbol 12-myristate 13-acetate indirectly activates Olfr866 by stimulating protein kinase C (PKC) activity. PKC, in turn, phosphorylates Olfr866, leading to its functional activation. This phosphorylation event initiates a cascade of intracellular events, allowing Olfr866 to participate in the signaling pathways and cellular processes associated with its role. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram is a direct activator of Olfr866 that functions by inhibiting phosphodiesterase (PDE) activity. By inhibiting PDE, Rolipram increases intracellular cAMP levels, which subsequently activate Olfr866 through the cAMP-dependent protein kinase A (PKA) pathway. This activation enables Olfr866 to engage in specific cellular responses and signal transduction cascades. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
D-erythro-Sphingosine-1-phosphate activates Olfr866 indirectly by binding to S1P receptors and initiating a downstream signaling pathway that involves G-protein coupled receptors (GPCRs). This activation eventually leads to the functional activation of Olfr866 and its involvement in the relevant cellular processes and signaling events. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin directly activates Olfr866 by increasing intracellular calcium levels. Elevated calcium levels trigger the activation of Olfr866 through calcium-dependent pathways, allowing the protein to participate in specific cellular responses and signaling cascades associated with its function. | ||||||
8-CPT-cAMP | 93882-12-3 | sc-201569 sc-201569A | 20 mg 100 mg | $85.00 $310.00 | 19 | |
Chlorophenylthio-cAMP (CPT-cAMP) is a direct activator of Olfr866 that mimics cAMP's action. It activates Olfr866 by binding to the protein's regulatory domain, inducing conformational changes that enhance its functional activity. This activation initiates downstream signaling pathways, enabling Olfr866 to perform its specific functions in cellular responses and signal transduction. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Dibutyryl-cAMP is a direct activator of Olfr866 that acts as a cell-permeable analog of cAMP. It activates Olfr866 by binding to the protein's regulatory domain, mimicking the action of endogenous cAMP and facilitating the protein's functional activation. This activation leads to Olfr866's involvement in the specific signaling pathways and cellular responses related to its function. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 (PGE2) indirectly activates Olfr866 by binding to its G-protein coupled receptor (GPCR), EP2. Activation of EP2 initiates downstream signaling pathways that result in the functional activation of Olfr866, allowing it to participate in specific cellular responses and signal transduction events associated with its role. | ||||||