Olfr814 Activators
Olfr814 is an olfactory receptor protein found in the olfactory system of organisms. Its primary function is to recognize and interact with specific odorant molecules, enabling the organism to perceive and distinguish different scents in its environment. Olfr814 plays a crucial role in the process of olfaction, where it acts as a molecular sensor for various odorants.
The activation of Olfr814 involves a complex set of molecular events. When an odorant molecule binds to the receptor, it triggers a conformational change in Olfr814. This conformational change initiates a signaling cascade that includes the activation of G-proteins, leading to an increase in intracellular cyclic adenosine monophosphate (cAMP) levels. Elevated cAMP levels, in turn, stimulate protein kinase A (PKA), which phosphorylates downstream target proteins. These phosphorylation events ultimately lead to the depolarization of olfactory sensory neurons, generating action potentials that convey the odorant information to the brain's olfactory cortex. In summary, Olfr814's activation is a well-defined process that enables organisms to detect and interpret specific odors, contributing to their overall sensory experience and environmental awareness.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol activates Olfr814 through the beta-adrenergic receptor, triggering cAMP production and subsequent enhancement of Olfr814 signaling. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP directly up-regulates Olfr814 by serving as a cAMP analog, promoting increased cAMP levels and heightened receptor activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Phorbol 12-myristate 13-acetate indirectly activates Olfr814 by modulating protein kinase C (PKC), which subsequently influences receptor signaling. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 indirectly activates Olfr814 by facilitating calcium influx, which can modulate intracellular pathways involved in receptor activation. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine indirectly activates Olfr814 by binding to its respective GPCR, leading to downstream signaling events that enhance receptor function. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 indirectly activates Olfr814 by interacting with its GPCR and initiating intracellular events that enhance receptor signaling. | ||||||
GABA | 56-12-2 | sc-203053 sc-203053A sc-203053B sc-203053C | 10 g 25 g 5 kg 10 kg | $64.00 $136.00 $459.00 $765.00 | 2 | |
GABA indirectly activates Olfr814 by binding to its GPCR and modulating downstream signaling pathways, ultimately enhancing receptor function. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine indirectly activates Olfr814 by binding to its GPCR and influencing intracellular pathways that amplify receptor activation responses. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine indirectly activates Olfr814 through its GPCR, initiating downstream events that enhance receptor signaling and function. | ||||||