Olfr714 Inhibitors
Olfr714, an olfactory receptor gene, is part of the sophisticated olfactory system in mammals, specifically mice. Olfactory receptors (ORs) like Olfr714 are G-protein-coupled receptors (GPCRs) predominantly expressed in the olfactory epithelium, where they play a vital role in detecting and distinguishing diverse odor molecules. Each olfactory receptor, including Olfr714, is tuned to perceive specific odorants, contributing to an organism's ability to recognize a wide array of smells.
The Olfr714 gene encodes a protein that, when bound by a specific odorant molecule, initiates a cascade of intracellular events leading to the generation of a nerve impulse. This signal is then transmitted to the brain, where it is interpreted as a distinct odor. The specificity and sensitivity of Olfr714 and other ORs allow for the detection of odorous compounds at various concentrations, enabling animals to respond to different environmental cues and stimuli.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog that incorporates into DNA and inhibits DNA methyltransferase, leading to demethylation and gene activation. While it can activate genes, it can also disrupt normal regulatory patterns, potentially inhibiting some genes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
An inhibitor of histone deacetylases (HDACs), enzymes that remove acetyl groups from an ε-N-acetyl lysine amino acid on a histone. Inhibition can lead to a change in gene expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Binds to DNA and interferes with the movement of RNA polymerase along the DNA molecule, inhibiting RNA synthesis and, subsequently, protein synthesis. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
A cyclic peptide that inhibits RNA polymerase II, thus inhibit mRNA synthesis and subsequent protein production. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II, thereby blocking mRNA synthesis. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds to DNA and inhibits RNA synthesis by inhibiting the binding of transcription factors to their respective DNA sequences. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A deoxycytidine analog that incorporates into DNA and inhibits DNA methyltransferases, leading to altered gene expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
An inhibitor of histone deacetylases (HDACs). By inhibiting HDACs, it can alter chromatin structure and affect gene expression. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Interferes with protein synthesis by inhibiting peptide bond formation. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Blocks the translation process by inhibiting the translocation step in protein synthesis, leading to mRNA degradation. | ||||||