Olfr702, a gene of significant scientific interest, plays a pivotal role in cellular processes and is closely associated with olfactory function. The gene encodes a specific protein with essential functions related to the perception of odorants. Olfr702 is primarily expressed in olfactory sensory neurons within the nasal epithelium, where it serves as a critical component of the olfactory signal transduction pathway. The function of Olfr702 revolves around its role as an odorant receptor, responsible for detecting and transducing odor signals into neural signals. Upon activation by odorant molecules, Olfr702 initiates a cascade of intracellular events that ultimately result in the perception of odors. This process involves the binding of odorants to Olfr702 receptors, triggering a series of biochemical reactions that lead to the generation of action potentials in olfactory sensory neurons. These action potentials are then transmitted to the brain, where they are interpreted as specific olfactory sensations, contributing to our sense of smell.
The activation of Olfr702 is a finely regulated process, crucial for accurate odor detection. General mechanisms of activation involve the interaction between odorant molecules and the Olfr702 receptor, which leads to a conformational change in the receptor protein. This change, in turn, triggers a signaling cascade within the olfactory sensory neuron, culminating in the transmission of the olfactory signal to the brain. Additionally, epigenetic regulation and modulation of Olfr702 transcription can influence its activation, allowing for the fine-tuning of olfactory responses. Overall, Olfr702 represents a fundamental component of the olfactory system, enabling us to perceive and distinguish a vast array of odors in our environment. Understanding the mechanisms of Olfr702 activation enhances our knowledge of sensory perception and the intricate processes underlying our sense of smell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates Olfr702 by directly stimulating adenylyl cyclase, leading to increased levels of intracellular cAMP. Elevated cAMP levels activate Olfr702 through a downstream signaling cascade, resulting in enhanced gene expression and cellular responses. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid acts as an activator of Olfr702 by binding to its specific nuclear receptor. This interaction enhances Olfr702's transcriptional activity, promoting gene expression and subsequent functional activation within the cell. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone activates Olfr702 by binding to glucocorticoid receptors, which translocate into the nucleus and modulate Olfr702 transcription. This direct activation leads to increased Olfr702 gene expression and functional activity. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
8-Bromo-cAMP activates Olfr702 by mimicking the action of cAMP. It directly influences the cAMP-dependent signaling pathway, resulting in the activation of Olfr702 and subsequent cellular responses associated with its function. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates Olfr702 by directly stimulating protein kinase C (PKC). This activation leads to the phosphorylation of Olfr702 and enhanced functional activity within the cell. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
Dimethyl Sulfoxide activates Olfr702 by influencing the epigenetic regulation of the gene. It can enhance Olfr702 promoter activity, resulting in increased gene expression and functional activation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium Butyrate activates Olfr702 by acting as a histone deacetylase inhibitor. This leads to histone hyperacetylation, which promotes Olfr702 transcription and functional activation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A activates Olfr702 by inhibiting histone deacetylase enzymes, leading to increased histone acetylation. This epigenetic modification enhances Olfr702 gene expression and subsequent functional activity within the cell. | ||||||
Budesonide | 51333-22-3 | sc-202980 sc-202980A sc-202980B sc-202980C | 50 mg 100 mg 200 mg 500 mg | $77.00 $88.00 $151.00 $343.00 | 3 | |
Budesonide activates Olfr702 by binding to glucocorticoid receptors, initiating a cascade of events that modulate Olfr702 transcription. This direct activation results in increased gene expression and functional activity. | ||||||
8-pCPT-2′-O-Me-cAMP | 634207-53-7 | sc-257020 | 1 mg | $300.00 | 5 | |
CPT-cAMP activates Olfr702 by stimulating the cAMP-dependent signaling pathway. It directly influences cAMP levels, leading to the activation of Olfr702 and subsequent cellular responses associated with its function. | ||||||