Date published: 2026-4-1

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Olfr5 Activators

Chemical activators of Olfr5, as proposed in this list, are based on typical activation mechanisms of olfactory receptors. These chemicals, such as Isoamyl acetate, Benzaldehyde, and Cinnamaldehyde, are hypothesized to interact directly with Olfr5, a G-protein-coupled receptor (GPCR). Upon binding to Olfr5, these compounds likely induce a conformational change in the receptor, initiating a cascade of intracellular events characteristic of GPCR activation. This process typically results in the production of cyclic AMP, a critical second messenger in olfactory signal transduction. The elevation in cyclic AMP is essential for converting the chemical signal into a neural signal, facilitating olfactory perception.

Other compounds like Limonene, Methyl salicylate, and Ethyl butyrate are also hypothesized to function similarly, binding to Olfr5 and activating the GPCR pathway. Each of these chemicals has a unique molecular structure that allows specific interaction with Olfr5, triggering the receptor's activation. This specificity is vital for the diverse range of odor detection and recognition in the olfactory system. The proposed activation of Olfr5 by these chemicals underscores the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$107.00
$225.00
(0)

Isopentyl acetate, with its banana-like aroma, may bind to Olfr5, activating the receptor through G protein-coupled receptor (GPCR) pathways, which lead to increased intracellular cyclic AMP levels, a crucial component for olfactory signal transduction.

Cinnamic Aldehyde

104-55-2sc-294033
sc-294033A
100 g
500 g
$104.00
$228.00
(0)

Cinnamic Aldehyde, with its cinnamon aroma, could interact with Olfr5, stimulating the receptor through GPCR pathways, resulting in increased cyclic AMP production, crucial for olfactory signal processing.

D-Limonene

5989-27-5sc-205283
sc-205283A
100 ml
500 ml
$84.00
$129.00
3
(1)

D-Limonene, characterized by its citrusy scent, may activate Olfr5 by binding to its active site, triggering GPCR signaling, and leading to an increase in cyclic AMP, vital for olfactory signal transduction.

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$47.00
$70.00
(1)

Methyl salicylate, with a wintergreen scent, might activate Olfr5 through direct receptor interaction, initiating GPCR pathway activation and an increase in cyclic AMP levels, necessary for olfactory signal processing.

Ethyl butyrate

105-54-4sc-214986
sc-214986A
1 kg
4 kg
$100.00
$210.00
(0)

Ethyl butyrate, known for its sweet, fruity scent, could activate Olfr5 by interacting with the receptor, triggering GPCR activation and subsequent cyclic AMP elevation, crucial for olfactory signaling.

Vanillin

121-33-5sc-251423
sc-251423A
100 g
500 g
$44.00
$124.00
1
(1)

Vanillin, characterized by its vanilla scent, may bind to Olfr5, activating the receptor and leading to GPCR pathway initiation, resulting in increased cyclic AMP, vital for olfactory signal processing.

4-Methoxybenzaldehyde

123-11-5sc-238884
sc-238884A
sc-238884B
sc-238884C
5 g
100 g
250 g
1 kg
$30.00
$42.00
$72.00
$124.00
(1)

4-Methoxybenzaldehyde, with a sweet, anise-like aroma, could activate Olfr5 through direct binding, triggering a cascade of intracellular events typical of GPCR activation, including increased cyclic AMP, necessary for olfactory signaling.

3-Ethoxy-4-hydroxybenzaldehyde

121-32-4sc-238538
100 g
$31.00
(0)

3-Ethoxy-4-hydroxybenzaldehyde, known for its rich vanilla scent, may activate Olfr5 by directly interacting with the receptor, inducing the GPCR pathway and resulting in elevated cyclic AMP, crucial for olfactory signaling.

Eugenol

97-53-0sc-203043
sc-203043A
sc-203043B
1 g
100 g
500 g
$32.00
$62.00
$218.00
2
(1)

Eugenol, with a clove-like aroma, could bind to Olfr5, activating the receptor and initiating the GPCR signaling cascade, leading to increased cyclic AMP levels, essential for olfactory signal transduction.

Octanal

124-13-0sc-250612
sc-250612A
25 ml
100 ml
$26.00
$34.00
(1)

Octanal, characterized by its citrusy and fatty scent, might activate Olfr5 through direct receptor interaction, leading to GPCR activation and a subsequent increase in cyclic AMP levels, crucial for olfactory signal processing.