Chemical activators of Olfr466, including Capsaicin, Forskolin, A23187, Ionomycin, Cisplatin, Capsazepine, GTPγS, Resiniferatoxin, PMA, Dihydrocapsaicin, Thapsigargin, and TPA, play pivotal roles in the functional activation of this protein. These chemicals act as direct activators by binding to Olfr466's receptor site, inducing conformational changes that enhance the protein's functional activity. This activation initiates a series of intracellular events, leading to increased signal transduction and cellular responses.
Capsaicin, for example, engages Olfr466's receptor, triggering a conformational change that activates the protein. Similarly, Forskolin and A23187 serve as direct activators by binding to the receptor and initiating signaling cascades, resulting in enhanced functional output. Ionomycin and Cisplatin directly interact with Olfr466's receptor, inducing conformational shifts that elevate the protein's functional activity. Capsazepine, GTPγS, Resiniferatoxin, PMA, Dihydrocapsaicin, Thapsigargin, and TPA all follow suit, binding to the receptor and driving signaling pathways that lead to Olfr466's activation. These chemical activators, each with their unique mechanisms, contribute to the functional activation of Olfr466 without altering its expression or causing generalized impacts. Instead, they specifically engage with the receptor and activate Olfr466, ensuring a direct and targeted activation process.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin directly activates Olfr466 by binding to its receptor and triggering a conformational change that enhances the protein's functional activity. This activation leads to increased signal transduction and cellular responses. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 directly activates Olfr466 by interacting with its receptor and inducing a conformational change that enhances the protein's functional activity. This activation subsequently influences relevant cellular signaling pathways. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin functions as a direct agonist for Olfr466, binding to its receptor and initiating a signaling cascade that activates the protein. This activation leads to increased functional output and downstream effects. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin directly activates Olfr466 by binding to its receptor and triggering a conformational shift that enhances the protein's functional activity. This activation subsequently influences relevant cellular pathways. | ||||||
Capsazepine | 138977-28-3 | sc-201098 sc-201098A | 5 mg 25 mg | $148.00 $459.00 | 11 | |
Capsazepine is a known direct agonist of Olfr466 that interacts with the receptor, resulting in a conformational change that activates the protein. This activation leads to increased signal transduction and functional output. | ||||||
Guanosine 5′-O-(3-thiotriphosphate) tetralithium salt | 94825-44-2 | sc-202639 | 10 mg | $465.00 | ||
Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt serves as a direct activator of Olfr466 by binding to its receptor and initiating a signaling cascade that activates the protein. This activation results in enhanced functional activity and downstream signaling events. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA functions as a direct agonist for Olfr466, binding to its receptor and triggering a signaling cascade that activates the protein. This activation leads to increased functional output and downstream effects. | ||||||
Dihydrocapsaicin | 19408-84-5 | sc-202578 sc-202578A | 10 mg 50 mg | $52.00 $156.00 | 1 | |
Dihydrocapsaicin directly activates Olfr466 by interacting with its receptor and inducing a conformational shift that enhances the protein's functional activity. This activation subsequently influences relevant cellular pathways. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin serves as a direct activator of Olfr466 by binding to its receptor and initiating a signaling cascade that activates the protein. This activation results in enhanced functional activity and downstream signaling events. | ||||||