Olfr310 Inhibitors
Olfr310 inhibitors encompass a range of chemical compounds that indirectly reduce the functional activity of this olfactory receptor through various mechanisms. Certain inhibitors alter prostaglandin synthesis, which by decreasing prostaglandin levels, may impact the modulation of olfactory receptors, thereby reducing Olfr310 activity. Another compound that desensitizes sensory neurons by engaging in thermosensory pathways can also impact olfactory signal transduction, leading to decreased sensitivity of Olfr310. Similarly, by activating competing sensory pathways, certain organic compounds known for their cooling properties can change the sensory landscape, resulting in the indirect inhibition of Olfr310 function. Furthermore, chemicals that block adenosine receptors or act on nicotinic acetylcholine receptors can modulate neurotransmitter release, which may lead to altered olfactory processing and reduced Olfr310 activity.
Other inhibitors function by directly interacting with the olfactory receptor or its surrounding membrane environment. Chemicals known to bind and block olfactory receptors can prevent the normal ligand-receptor interactions necessary for Olfr310 activation. Surfactants may disrupt receptor membranes, altering the receptor conformation or environment, which can lead to decreased Olfr310 activity. Additionally, monoterpene compounds can inhibit normal ligand binding to Olfr310, while substances that affect membrane dynamics or disrupt cellular membranes can alter the receptor's membrane environment, preventing proper signal transmission.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $53.00 $88.00 | 6 | |
Inhibits cyclooxygenase enzymes (COX-1 and COX-2), leading to a reduction in prostaglandin synthesis. Prostaglandins can modulate olfactory receptor function, and thus, the inhibition of their synthesis by Ibuprofen could indirectly decrease the functional activity of Olfr310. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
An active component of chili peppers that binds to the transient receptor potential vanilloid 1 (TRPV1) receptor, which is involved in the sensation of heat and pain. Binding to TRPV1 by Capsaicin may lead to desensitization of sensory neurons that could impact olfactory signal transduction, thereby indirectly inhibiting Olfr310. | ||||||
(−)-Menthol | 2216-51-5 | sc-202705 sc-202705A | 1 g 50 g | $20.00 $41.00 | 2 | |
An organic compound with a characteristic minty odor that is known to activate transient receptor potential melastatin 8 (TRPM8) channels, involved in thermosensation and cooling sensation. Activation of TRPM8 can lead to altered sensory neuron responses, which could indirectly inhibit the function of Olfr310 by changing the olfactory sensory landscape. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
A central nervous system stimulant that blocks adenosine receptors. Adenosine can modulate olfactory signaling, and by blocking its receptors, Caffeine may alter the perception of odors and indirectly inhibit the activity of Olfr310. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
A chemical compound that can bind to and block olfactory receptors. By binding to these receptors, Copper sulfate may prevent ligand binding and activation of Olfr310, leading to its inhibition. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Known to interfere with olfactory receptor function by binding to receptor sites or related ion channels. Zinc sulfate may block the activation of Olfr310, suppressing its functional activity. | ||||||
Sodium dodecyl sulfate | 151-21-3 | sc-264510 sc-264510A sc-264510B sc-264510C | 25 g 100 g 500 g 1 kg | $78.00 $119.00 $419.00 $603.00 | 11 | |
A surfactant that can affect membrane proteins and potentially disrupt the olfactory receptor membranes. Such disruption could inhibit the functional activity of Olfr310 by altering its receptor conformation or environment. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
A monocyclic monoterpene that has been shown to interact with olfactory receptors. By binding to certain sites, D-Limonene could inhibit the normal ligand-receptor interaction of Olfr310, reducing its activity. | ||||||
Chloroform | 67-66-3 | sc-239527A sc-239527 | 1 L 4 L | $112.00 $204.00 | 1 | |
Can disrupt cellular membranes and protein function. By altering the membrane environment of olfactory receptors, Chloroform could inhibit the activation and signaling of Olfr310. | ||||||