NPW inhibitors refer to a class of chemical compounds designed to modulate the activity of the Neuropeptide W (NPW) system within the central nervous system. Neuropeptide W is a neuropeptide that plays a crucial role in regulating various physiological functions, primarily related to appetite, energy balance, and stress responses. The development of NPW inhibitors aims to explore the intricate mechanisms of this neuropeptide system and its implications in understanding neural circuitry and behavior.These inhibitors are typically small molecules or peptides designed to interact with specific components of the NPW signaling pathway. They may function by binding to NPW receptors, such as NPW1R and NPW2R, to either block or enhance their activation.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
Tyrosine kinase inhibitor targeting BCR-ABL, used for the therpy of chronic myeloid leukemia (CML). | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor that inhibits cell growth and is used in immunosuppressive therapy and some cancer. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Forms DNA cross-links, disrupting DNA replication and transcription, used in chemotherapy for various cancers. | ||||||
Omeprazole | 73590-58-6 | sc-202265 | 50 mg | $67.00 | 4 | |
Proton pump inhibitor that reduces stomach acid production by blocking the H+/K+ ATPase enzyme in gastric cells. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Selective estrogen receptor modulator (SERM) used for breast cancer therapy by competing with estrogen. | ||||||
Donepezil | 120014-06-4 | sc-279006 | 10 mg | $74.00 | 3 | |
Acetylcholinesterase inhibitor, used in Alzheimer's disease to increase acetylcholine levels in the brain. | ||||||
Raltegravir | 518048-05-0 | sc-364600 sc-364600A sc-364600B sc-364600C sc-364600D | 5 mg 50 mg 100 mg 500 mg 1 g | $100.00 $821.00 $1229.00 $2861.00 $4085.00 | 21 | |
HIV integrase inhibitor, prevents viral DNA integration into the host genome, used in antiretroviral therapy. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Proteasome inhibitor that disrupts protein degradation, used in multiple myeloma and some lymphomas. | ||||||
Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $87.00 $135.00 $293.00 $505.00 $3827.00 | 42 | |
Epidermal growth factor receptor (EGFR) inhibitor, used in non-small cell lung cancer by inhibiting EGFR signaling. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Activates AMP-activated protein kinase (AMPK), reducing glucose production and improving insulin sensitivity. | ||||||