NPW Activators
Neuropeptide W (NPW) is a neuropeptide that operates as a signaling molecule within the central nervous system (CNS). It is encoded in humans by the NPW gene. As a member of the neuropeptide family, NPW is involved in a variety of central regulatory processes, including the modulation of food intake, energy homeostasis, pain perception, and the hormonal axis. NPW acts through G-protein-coupled receptors, specifically GPR7 and GPR8, which are implicated in the regulation of endocrine functions and the body's response to stress.
The peptide is produced in response to physiological stimuli and has a role in neuroendocrine signaling. Its distribution in the brain suggests a significant role in the modulation of emotional states and the body's stress axis, influencing behaviors such as anxiety and depression. The peptide also participates in the regulation of food intake, suggesting a role in energy balance and metabolism.Research into NPW has highlighted its involvement in complex physiological processes, including the regulation of blood pressure and the sleep-wake cycle. Its precise functions are still being unraveled, with studies investigating its role in pathological states, aiming to understand its contribution to disorders related to the CNS and metabolic diseases.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin stimulates adenylate cyclase, potentially increasing cAMP and protein expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C which could influence gene transcription and protein expression. | ||||||
Kainic acid monohydrate | 58002-62-3 | sc-269283 | 10 mg | $270.00 | ||
Kainic acid, as an excitatory agent, may induce neuronal activity and neuropeptide expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can impact glycogen synthase kinase 3 (GSK-3) and influence gene expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid acts as a histone deacetylase inhibitor, potentially affecting chromatin and gene expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is an inhibitor of PI3K, impacting signaling pathways and possibly protein expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 also inhibits PI3K and can influence signaling cascades related to protein expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Beta-estradiol can modulate gene expression through estrogen receptor signaling pathways. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a glucocorticoid that may influence gene transcription and protein synthesis. | ||||||