Npcd inhibitors are a class of chemical compounds that inhibit enzymes or proteins involved in specific biochemical pathways related to cellular processes, particularly those associated with cellular death and metabolic regulation. These inhibitors often interact with proteins or enzymes that play key roles in the regulation of cell signaling pathways, such as apoptosis (programmed cell death), autophagy (cellular degradation and recycling), and other stress response mechanisms. The term "Npcd" typically denotes proteins or pathways linked to these cellular functions. By binding to and inhibiting these proteins or enzymes, Npcd inhibitors can modulate various cellular processes, affecting the way cells respond to stress, environmental signals, or cellular damage. Their structures vary widely, as they are designed to target specific proteins or enzymes with a high degree of specificity and binding affinity, allowing them to selectively interfere with the function of the target molecules.
Structurally, Npcd inhibitors are characterized by a diverse range of chemical scaffolds that confer the ability to bind to their target proteins with high specificity. These compounds may include small molecules, peptides, or even larger macromolecules, depending on the nature of the target they are designed to inhibit. They often contain functional groups that facilitate strong interactions with the active site or regulatory domains of their target proteins, such as hydrogen bonding, hydrophobic interactions, or ionic bonding. Their design is typically influenced by the structure of the target protein, with the aim of maximizing binding efficiency and minimizing off-target effects. The unique binding characteristics of Npcd inhibitors enable them to act as powerful tools for the study of cellular pathways, allowing researchers to dissect the roles of specific proteins in cellular processes and better understand how cells regulate their survival, death, and adaptation to various conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase (HDAC) inhibitor, affecting chromatin structure and gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor, altering chromatin dynamics and potentially impacting genes related to Npcd. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
A cyclic peptide and HDAC inhibitor with potential effects on gene regulation. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
A potent HDAC inhibitor, affecting various cellular pathways, including those related to chromatin. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Functions as an HDAC inhibitor and primarily used as an anticonvulsant. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
A selective HDAC inhibitor, potentially impacting gene expression relevant to Npcd. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $153.00 $561.00 | ||
An HDAC inhibitor with effects on chromatin structure and gene expression. | ||||||
PI3K/HDAC Inhibitor | 1339928-25-4 | sc-364584 sc-364584A | 5 mg 10 mg | $340.00 $462.00 | ||
A dual inhibitor of HDAC and PI3K, affecting multiple pathways that could intersect with Npcd activity. | ||||||
CI 994 | 112522-64-2 | sc-205245 sc-205245A | 10 mg 50 mg | $97.00 $525.00 | 1 | |
An HDAC inhibitor, potentially influencing chromatin dynamics and related protein functions. | ||||||
JNJ-26481585 | 875320-29-9 | sc-364515 sc-364515A | 5 mg 50 mg | $321.00 $1224.00 | ||
An HDAC inhibitor with broad-spectrum activity, possibly affecting chromatin-related proteins. | ||||||