NMDAε1 Inhibitors belong to a distinct chemical class known for their modulation of a crucial neurological receptor called the N-Methyl-D-Aspartate epsilon 1 receptor (NMDAε1). This receptor is part of the NMDA receptor family, which plays a pivotal role in synaptic plasticity and the transmission of excitatory signals in the central nervous system (CNS). NMDA receptors are composed of multiple subunits, and NMDAε1 is a specific subunit variant that has garnered considerable interest due to its involvement in various neurological processes. NMDAε1 Inhibitors are characterized by their ability to bind to the NMDAε1 receptor and modulate its activity. By binding to this receptor, these inhibitors can exert a regulatory influence on synaptic transmission and neuronal excitability. The modulation of NMDAε1 activity is crucial for maintaining the delicate balance between synaptic strengthening and weakening, which underlies learning, memory formation, and overall neural network stability. Chemical compounds falling within the NMDAε1 Inhibitor class often possess unique structural features that enable them to interact selectively with the NMDAε1 subunit. This selectivity is essential to avoid interfering with other NMDA receptor subunits, thereby ensuring precise control over the neural processes mediated by NMDAε1.
Researchers and scientists are actively investigating the pharmacological and physiological implications of NMDAε1 Inhibitors. These compounds have the potential to shed light on the intricate mechanisms governing synaptic plasticity and offer insights into the fundamental processes that shape neural circuits. By understanding the ways in which NMDAε1 Inhibitors interact with the NMDA receptor family, researchers aim to uncover novel strategies for influencing synaptic transmission and neuronal function. This class of inhibitors holds promise as a tool for advancing our understanding of neural network dynamics and may pave the way for future discoveries in the field of neuroscience.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Memantine hydrochloride | 41100-52-1 | sc-203628 | 50 mg | $68.00 | 4 | |
memantine acts as a moderate-level, uncompetitive antagonist of NMDA receptors. | ||||||
Dextromethorphan | 125-71-3 | sc-278927 sc-278927A sc-278927B | 10 g 100 g 500 g | $174.00 $1133.00 $5106.00 | 3 | |
An ingredient commonly found in cough medicines, it can act as an NMDA receptor antagonist at higher doses. | ||||||
Lamotrigine | 84057-84-1 | sc-201079 sc-201079A | 10 mg 50 mg | $118.00 $476.00 | 1 | |
Originally developed as an antiepileptic drug, lamotrigine has also been found to have NMDA receptor-blocking properties. | ||||||
Eliprodil | 119431-25-3 | sc-203939 sc-203939A | 10 mg 50 mg | $145.00 $510.00 | ||
NMDA receptor-blocking properties. | ||||||
CGS 19755 | 110347-85-8 | sc-203882 sc-203882A | 10 mg 50 mg | $185.00 $781.00 | ||
selfotel was one of the early investigational NMDA receptor antagonists explored for potential neuroprotective effects in stroke. | ||||||