nm23-H6 Activators
nm23-H6, also known as NME6, is a member of the nm23 family of nucleoside diphosphate kinases. Its precise roles in cellular signaling and processes are multifaceted, and the understanding of its modulators remains incomplete.
For instance, Lithium chloride is an activator of the Wnt signaling pathway, a key process that can engage with nm23-H6 functions. Similarly, Forskolin is known to increase intracellular cAMP levels, affecting many downstream signaling processes that can potentially be related to nm23-H6. Chemicals like LY294002 and Wortmannin, which act as PI3K inhibitors, provide a link between nm23-H6 and the PI3K/AKT signaling cascade, an essential pathway in cell growth and survival. Another compound, Rapamycin, which is an mTOR inhibitor, can influence cellular growth pathways, underlining its possible interplay with nm23-H6. The range of chemicals, from PKC activators like PMA to calcium ionophores like Ionomycin, illustrates the expansive network of signaling pathways that nm23-H6 might be associated with in cellular environments.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Activates Wnt signaling, a pathway that can intersect with nm23-H6 activities. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases intracellular cAMP levels, which can influence nm23-H6 activity through related signaling. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
β-adrenergic receptor agonist; can modulate cAMP pathways that may be associated with nm23-H6. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates Protein Kinase C (PKC); can influence cellular pathways that nm23-H6 is involved in. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor; modulation of the PI3K/AKT pathway can influence processes associated with nm23-H6. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor; its impact on cytoskeletal dynamics can relate to pathways in which nm23-H6 operates. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
CDK inhibitor that affects cell cycle and differentiation, possibly influencing nm23-H6. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor; affects cellular growth pathways that may be relevant to nm23-H6. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor; modulation of the PI3K/AKT signaling can be relevant to nm23-H6's role in cells. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
A calcium ionophore; elevates intracellular calcium levels, possibly influencing signaling pathways associated with nm23-H6. | ||||||