Nlrp12 Activators
The first group of activators, including Parthenolide, Sulforaphane, and Curcumin, exert their effects on Nlrp12 by modulating key inflammatory pathways. Parthenolide's inhibition of NF-κB, Sulforaphane's activation of the Nrf2 pathway, and Curcumin's modulation of various signaling pathways, including NF-κB, indirectly enhance Nlrp12's regulatory function in inflammation. Resveratrol, with its anti-inflammatory properties, and aspirin, through its well-known effects on inflammation and cytokine production, also contribute to modulating the functional activity of Nlrp12.
Additionally, compounds like, Quercetin, and Vitamin D, known for their roles in modulating immune responses and inflammation, can indirectly enhance Nlrp12 activity. Quercetin's antioxidant properties, and Vitamin D's modulation of immune responses all play a role in influencing Nlrp12's activity in inflammatory pathways. Furthermore, EGCG, Indomethacin, Ibuprofen, and Anakinra, through their respective roles in antioxidant responses, inflammatory pathway modulation, and cytokine signaling, highlight the diverse mechanisms through which Nlrp12's function in innate immunity and inflammation can be enhanced.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane activates the Nrf2 pathway, which is involved in cellular antioxidant responses. This activation can indirectly enhance Nlrp12 activity in pathways related to oxidative stress and inflammation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin modulates various signaling pathways, including NF-κB. Its modulation can indirectly enhance Nlrp12 activity by influencing inflammatory pathways where Nlrp12 is involved. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, through its anti-inflammatory properties, can potentially enhance Nlrp12 activity by modulating inflammatory responses and cytokine production. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
Aspirin, a nonsteroidal anti-inflammatory drug, can potentially enhance Nlrp12 activity by modulating inflammatory pathways and cytokine production, central to Nlrp12's function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, an antioxidant, may influence Nlrp12 activity by modulating cellular oxidative stress levels and affecting inflammatory pathways. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D can modulate immune responses and has been linked to inflammatory pathway regulation, potentially enhancing Nlrp12 activity in these processes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a major component of green tea, has antioxidant properties that could indirectly enhance Nlrp12 activity in processes involving oxidative stress and inflammation. | ||||||
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $28.00 $37.00 | 18 | |
Indomethacin, a nonsteroidal anti-inflammatory drug, can potentially enhance Nlrp12 activity by affecting inflammatory pathways and cytokine production. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $52.00 $86.00 | 6 | |
Ibuprofen, another nonsteroidal anti-inflammatory drug, can influence inflammatory pathways, potentially enhancing Nlrp12's role in these processes. | ||||||
Anakinra | 143090-92-0 | sc-507486 | 10 mg | $795.00 | ||
Anakinra, an IL-1 receptor antagonist, could indirectly enhance Nlrp12 activity by modulating cytokine signaling pathways, which are integral to Nlrp12's function. | ||||||