NKp46 Activators
The list provided above includes chemicals that can indirectly influence the activity of NKp46 by modulating natural killer (NK) cell functions or related immune pathways. These chemicals are not direct activators of NKp46 but may impact its activity through their effects on the immune system. For instance, immunomodulatory drugs like Lenalidomide, Thalidomide, and Pomalidomide can affect the functioning of NK cells, which may in turn influence NKp46 activity. These drugs are known to alter the immune response, enhancing or modifying the activity of NK cells.
Additionally, compounds like Bortezomib and Azacytidine, used primarily in cancer therapy, can also modulate immune responses. Their impact on the immune system can indirectly affect NK cell functions, including the activity of receptors like NKp46. Natural compounds such as Resveratrol, Curcumin, Sulforaphane, and Epigallocatechin Gallate (EGCG) have been studied for their immunomodulatory properties. These substances can alter immune cell behavior, including that of NK cells, which may have downstream effects on NKp46 activity Furthermore, agents like Imiquimod, known for modifying immune responses, particularly in the context of antiviral and antitumor immunity, may also have implications for NK cell function and NKp46. Lastly, Vitamin D3, which plays a role in immune regulation, could influence NK cell functions and, as a result, NKp46 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $111.00 $357.00 | 8 | |
Thalidomide, known for modulating immune responses, might influence NK cell activity and indirectly NKp46. | ||||||
Pomalidomide | 19171-19-8 | sc-364593 sc-364593A sc-364593B sc-364593C sc-364593D sc-364593E | 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $143.00 $312.00 $468.00 $1248.00 $1997.00 | 1 | |
Pomalidomide can modulate immune responses, possibly affecting NK cell functions and NKp46. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib can affect immune responses and may indirectly influence NKp46 through NK cell modulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Azacytidine, by affecting immune response regulation, might have an indirect effect on NKp46 activity. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Imiquimod, an immune response modifier, may indirectly impact NK cell functions and NKp46 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to modulate immune responses, which could indirectly affect NKp46. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate immune system components, potentially influencing NK cell activity and NKp46. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a component of green tea, has immunomodulatory effects that could influence NK cell activity and NKp46. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Disulfiram, through its immunomodulatory effects, might have an indirect influence on NKp46 activity. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 has roles in immune regulation and could indirectly affect NK cell functions and NKp46. | ||||||