NIRF Activators
NIRF Activators refers to a category of compounds that can potentially influence the function of the NIRF protein. These compounds often exert their effects by interacting with various cellular pathways and processes linked to NIRF's role. For instance, proteasome inhibitors like MG132 and Epoxomicin can potentially influence the function of NIRF in protein ubiquitination, leading to an increase in ubiquitinated proteins levels. This gives us insights into NIRF's role in protein degradation and turnover.
On the other hand, compounds like Etoposide, Doxorubicin and Camptothecin induce DNA damage, potentially affecting the DNA repair pathway in which NIRF is involved. By studying the effects of these compounds on NIRF function, we can better understand its role in the maintenance of genomic stability. Similarly, Hydroxyurea and Nocodazole can influence the cellular pathways involving NIRF, due to their effects on DNA replication and cell cycle progression, respectively. Understanding these compounds and their effects allows us to better comprehend the role of NIRF in various cellular processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 is a proteasome inhibitor that can increase the level of proteins ubiquitinated by NIRF. | ||||||
Epoxomicin | 134381-21-8 | sc-201298C sc-201298 sc-201298A sc-201298B | 50 µg 100 µg 250 µg 500 µg | $137.00 $219.00 $449.00 $506.00 | 19 | |
Epoxomicin is another proteasome inhibitor that can potentially influence NIRF's function in protein ubiquitination. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide induces DNA damage, which can activate the DNA repair pathway in which NIRF is involved. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin is a DNA intercalating agent that can induce DNA damage, potentially affecting the DNA repair pathway involving NIRF. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Hydroxyurea induces replication stress, which can lead to activation of certain cellular pathways involving NIRF. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole interferes with microtubule function leading to cell cycle arrest, potentially influencing NIRF's role in cell cycle progression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin induces DNA damage, potentially affecting the DNA repair pathway involving NIRF. | ||||||