The chemical class of Neurocan Activators encompasses a diverse range of compounds that could potentially influence the activity of Neurocan indirectly. Neurocan plays a pivotal role in the central nervous system by participating in cell-matrix interactions, influencing cell adhesion, proliferation, and migration. The modulation of Neurocan is intricately linked to the dynamics of the extracellular matrix, cellular signaling pathways, and overall tissue homeostasis.Compounds such as TGF-β Activators and Cytokine Inhibitors demonstrate the potential to influence Neurocan activity indirectly through their roles in modulating key signaling pathways. For example, TGF-β Activators like Dorsomorphin can affect BMP signaling, thereby potentially altering TGF-β pathways which are known to influence Neurocan expression. Similarly, EGF, known for stimulating cell proliferation and migration, could also play a role in modulating Neurocan expression.
Additionally, the inclusion of compounds that impact the composition and dynamics of the extracellular matrix, such as Hyaluronic Acid, Ascorbic Acid, and Matrix Metalloproteinase Inhibitors, reflects the complex interaction between Neurocan and its surrounding matrix. Ascorbic Acid, essential for collagen synthesis, and Hyaluronic Acid, a major ECM component, highlight the interplay between ECM components and Neurocan. Furthermore, signaling molecules like Lithium Chloride, Dexamethasone, Sulforaphane, and Curcumin, with their broad effects on various pathways such as Wnt signaling and gene expression modulation, provide insights into the indirect mechanisms through which Neurocan can be influenced.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
Inhibits BMP signaling, potentially affecting TGF-β pathways which could indirectly influence Neurocan expression. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $208.00 | ||
A major component of the ECM, could influence Neurocan activity by altering ECM dynamics. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Essential for collagen synthesis, might influence ECM composition and indirectly affect Neurocan. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in cell differentiation and growth, potentially affecting Neurocan expression in the nervous system. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits TGF-β signaling, potentially influencing Neurocan expression through altered cytokine signaling. | ||||||
GM 6001 | 142880-36-2 | sc-203979 sc-203979A | 1 mg 5 mg | $77.00 $270.00 | 55 | |
Influences ECM remodeling, could indirectly affect Neurocan activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences Wnt signaling pathway, potentially affecting Neurocan expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid influencing various signaling pathways, might modulate Neurocan expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Affects gene expression and cellular signaling, potentially influencing Neurocan activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Influences various signaling pathways, potentially modulating Neurocan expression. | ||||||