Date published: 2025-10-25

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Nebulin Inhibitors

Nebulin Inhibitors represent a distinctive class of chemical compounds primarily known for their role in modulating the activity of nebulin, a large cytoskeletal protein found in skeletal muscle. Nebulin is a critical component in the architecture of sarcomeres, the basic units of muscle fibers, and plays a vital role in regulating muscle contraction. Inhibitors targeting nebulin have garnered significant attention due to their potential impact on cellular processes involved in muscle function. The structural characteristics of nebulin inhibitors are designed to interact specifically with nebulin molecules, influencing their conformation or interfering with their binding to other cellular components. This class of compounds typically exhibits a high degree of selectivity, honing in on nebulin without significantly affecting other cellular processes.

Research on nebulin inhibitors has provided valuable insights into the intricate mechanisms governing muscle contraction and the broader context of cellular signaling. By elucidating the molecular interactions between nebulin and its inhibitors, scientists aim to unravel the complexities of muscle biology and potentially identify novel avenues for intervention in conditions related to muscle dysfunction. The development of nebulin inhibitors is an ongoing area of investigation, with researchers exploring the precise ways in which these compounds impact the structural and functional aspects of nebulin within the cellular milieu. Understanding the intricacies of nebulin inhibition may open new avenues for targeted interventions in muscle-related disorders, although the translational applications of this research are still in the early stages of exploration.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(S)-(−)-Blebbistatin

856925-71-8sc-204253
sc-204253A
sc-204253B
sc-204253C
1 mg
5 mg
10 mg
25 mg
$71.00
$260.00
$485.00
$949.00
(2)

Blebbistatin is a small molecule inhibitor that can inhibit non-muscle myosin II and indirectly influence Nebulin's function.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$145.00
$442.00
64
(4)

Cytochalasin D is an actin polymerization inhibitor that can affect the structure of actin filaments that Nebulin binds to.

Latrunculin A, Latrunculia magnifica

76343-93-6sc-202691
sc-202691B
100 µg
500 µg
$260.00
$799.00
36
(2)

Latrunculin A is a macrolide toxin that can bind to actin monomers and prevent their polymerization, indirectly influencing Nebulin's function.

Jasplakinolide

102396-24-7sc-202191
sc-202191A
50 µg
100 µg
$180.00
$299.00
59
(1)

Jasplakinolide is a cyclodepsipeptide that promotes actin polymerization and stabilize actin filaments, thus could potentially affect Nebulin's role.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

Paclitaxel stabilizes microtubules and prevents their depolymerization, which can indirectly affect the function of Nebulin.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$58.00
$83.00
$140.00
$242.00
38
(2)

Nocodazole disrupts microtubule dynamics by inducing their depolymerization, indirectly influencing the function of Nebulin.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

Y-27632 is an inhibitor of ROCK (Rho-associated protein kinase), a kinase involved in muscle contraction and potentially affecting Nebulin's function.

Fasudil, Monohydrochloride Salt

105628-07-7sc-203418
sc-203418A
sc-203418B
sc-203418C
sc-203418D
sc-203418E
sc-203418F
10 mg
50 mg
250 mg
1 g
2 g
5 g
10 g
$18.00
$32.00
$85.00
$165.00
$248.00
$486.00
$910.00
5
(1)

Fasudil is a potent Rho-kinase inhibitor and vasodilator that can indirectly influence Nebulin's function.

ML-7 hydrochloride

110448-33-4sc-200557
sc-200557A
10 mg
50 mg
$89.00
$262.00
13
(1)

ML-7 inhibits myosin light chain kinase (MLCK), a key regulator of muscle contraction, potentially affecting Nebulin's function.

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$48.00
$122.00
$432.00
$812.00
4
(1)

Wiskostatin is a non-competitive inhibitor of the neural Wiskott-Aldrich syndrome protein (N-WASP), a regulator of actin polymerization.