Nanos3 activators are a specialized group of chemical compounds that interact with the Nanos3 protein, a member of the Nanos protein family which is known for its role in various cellular and developmental processes. These activators are designed to promote the functional activity of Nanos3 by increasing its stability, enhancing its interaction with other cellular components, or by facilitating its proper localization within the cell. The mode of action of Nanos3 activators could be direct, through binding to the Nanos3 protein itself, or indirect, by influencing other molecules within the cellular environment that affect the function of Nanos3. The structural design of these molecules is often a result of comprehensive research that includes the study of the Nanos3 protein's three-dimensional configuration, the identification of its active sites, and the understanding of the molecular pathways in which Nanos3 is involved.
To efficiently activate Nanos3, the chemical structure of these activators usually features specific functional groups or scaffolds that have been optimized for interaction with the protein or its associated molecular partners. The development of Nanos3 activators typically entails the incorporation of molecular features that can enhance the binding affinity and specificity towards Nanos3. These features may include hydrogen bond donors and acceptors, hydrophobic regions, and charged groups that can participate in a variety of non-covalent interactions with the target protein. The chemical complexity of Nanos3 activators can vary widely; some might closely resemble natural ligands or substrates of the protein, while others might be entirely synthetic constructs that have been found to modulate the activity of Nanos3 through high-throughput screening or rational drug design. The precise arrangement of atoms within these activators is crucial, as it determines the efficacy with which these molecules can engage with the Nanos3 protein and influence its function.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can induce developmental genes during differentiation, and therefore might theoretically upregulate Nanos3 in early germ cells. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is crucial for DNA synthesis. Theoretically, it could upregulate Nanos3 during DNA replication in germ cell development. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol can upregulate genes via antioxidant response pathways. It might indirectly induce Nanos3 expression during germ cell differentiation. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
β-Estradiol can induce gene expression in sex-differentiating tissues. It might theoretically induce Nanos3 expression in female germ cells. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone can induce gene expression via glucocorticoid receptors. It might indirectly upregulate Nanos3 expression during stress responses. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
(-)-Epigallocatechin Gallate can induce genes involved in antioxidant response. It might indirectly induce Nanos3 expression via these pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can induce gene expression via antioxidant and anti-inflammatory pathways. It might indirectly induce Nanos3 expression via these pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein can induce gene expression in sex-differentiating tissues. It might theoretically induce Nanos3 expression in early germ cells. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, as a HDAC inhibitor, can lead to gene induction. It might induce Nanos3 expression by relaxing chromatin structure. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, as a HDAC inhibitor, can induce gene expression. It might induce Nanos3 expression by relaxing chromatin structure. |