Mx1 Inhibitors
Mx1 inhibitors represent a distinct class of compounds within the realm of molecular pharmacology. These inhibitors are primarily designed to target and modulate the activity of the Mx1 protein, which is an integral component of the innate immune system. Mx1, also known as myxovirus resistance protein 1, plays a pivotal role in the host's defense against viral infections, particularly those caused by RNA viruses. Structurally, Mx1 belongs to the GTPase superfamily, and its activation leads to a cascade of immune responses that help restrict viral replication and dissemination within the host organism.
Mx1 inhibitors are designed to interfere with the normal functioning of the Mx1 protein, thereby exerting a regulatory influence over its antiviral activities. These inhibitors are typically small molecules or compounds with specific binding properties that allow them to interact with Mx1 and modulate its GTPase activity or other essential functions. By disrupting the normal function of Mx1, these inhibitors can potentially hinder the host's innate immune response to viral infections.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1-Adamantylamine | 768-94-5 | sc-251475 sc-251475A | 1 g 25 g | $38.00 $144.00 | ||
Inhibits the viral M2 ion channel, preventing viral uncoating. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $62.00 $108.00 $210.00 | 1 | |
Impairs viral RNA synthesis by causing mutations and errors. | ||||||
Oseltamivir | 196618-13-0 | sc-507283 | 100 g | $324.00 | ||
Blocks neuraminidase, hindering viral release from host cells. | ||||||
Zanamivir | 139110-80-8 | sc-208495 | 1 mg | $265.00 | 6 | |
Similar to oseltamivir, it inhibits neuraminidase activity. | ||||||
Baloxavir marboxil | 1985606-14-1 | sc-507295 | 100 mg | $132.00 | ||
Inhibits cap-dependent endonuclease, disrupting mRNA synthesis. | ||||||
Raltegravir | 518048-05-0 | sc-364600 sc-364600A sc-364600B sc-364600C sc-364600D | 5 mg 50 mg 100 mg 500 mg 1 g | $100.00 $821.00 $1229.00 $2861.00 $4085.00 | 21 | |
Inhibits the viral integrase enzyme, preventing genome integration. | ||||||
S/GSK1349572 | 1051375-16-6 | sc-364605 sc-364605B sc-364605A | 5 mg 50 mg 200 mg | $367.00 $1484.00 $4131.00 | ||
Similar to raltegravir, it inhibits HIV integrase activity. | ||||||
Sofosbuvir | 1190307-88-0 | sc-482362 | 25 mg | $143.00 | 1 | |
Acts as a nucleotide analog, inhibiting hepatitis C virus RNA polymerase. | ||||||
Simeprevir | 923604-59-5 | sc-473928 sc-473928A | 5 mg 50 mg | $296.00 $2040.00 | ||
Inhibits the hepatitis C virus NS3/4A protease, preventing cleavage of viral proteins. | ||||||