Mutagenesis Research Chemicals
Items 81 to 90 of 172 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2′-Deoxyuridine 5′-monophosphate disodium salt | 42155-08-8 | sc-214068 sc-214068A | 100 mg 250 mg | $261.00 $497.00 | ||
2'-Deoxyuridine 5'-monophosphate disodium salt serves as a pivotal tool in mutagenesis research, exhibiting a propensity for phosphorylation and subsequent incorporation into nucleic acids. Its structural features facilitate interactions with DNA polymerases, influencing replication processes and error rates. The compound's ability to modulate nucleotide pools can alter cellular responses to DNA damage, making it essential for dissecting mutagenic pathways and understanding genetic stability. | ||||||
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $61.00 $128.00 | 5 | |
Dichloroacetic acid is a potent research chemical in mutagenesis studies, known for its ability to disrupt cellular metabolic pathways. Its unique structure allows for specific interactions with key enzymes involved in cellular respiration and fatty acid metabolism. This compound can induce oxidative stress, leading to DNA damage and subsequent mutagenic effects. By influencing gene expression and cellular signaling, it provides insights into the mechanisms of mutagenesis and genetic variability. | ||||||
N-Ethylethylenediamine | 110-72-5 | sc-281074 sc-281074A | 10 g 25 g | $43.00 $84.00 | ||
N-Ethylethylenediamine serves as a significant tool in mutagenesis research, characterized by its ability to form stable complexes with nucleophiles. This compound can facilitate the formation of reactive intermediates, which may interact with DNA, leading to alterations in genetic material. Its unique bifunctional nature allows it to engage in diverse reaction pathways, influencing cellular processes and providing a deeper understanding of mutagenic mechanisms and their implications in genetic studies. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
Sorafenib is a multi-kinase inhibitor that plays a significant role in mutagenesis research by targeting various signaling pathways involved in cell proliferation and survival. Its unique ability to inhibit RAF kinases and VEGFR contributes to altered cellular signaling, impacting gene expression and DNA repair mechanisms. The compound's interactions with specific protein kinases can induce oxidative stress, leading to DNA damage and subsequent mutagenic effects, making it a valuable tool for studying genetic instability. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin is a potent agent in mutagenesis research, known for its ability to bind to DNA, forming cross-links that disrupt replication and transcription processes. This compound interacts primarily with the N7 position of guanine, leading to the formation of intrastrand cross-links that hinder cellular repair mechanisms. Its unique reactivity and kinetic properties allow for the exploration of DNA damage response pathways, providing insights into mutagenic processes and their biological consequences. | ||||||
2-Bromo-1,4-naphthoquinone | 2065-37-4 | sc-225182 | 10 g | $90.00 | ||
2-Bromo-1,4-naphthoquinone serves as a potent mutagenesis research chemical, exhibiting unique reactivity through its electrophilic nature. It can form adducts with nucleophilic sites in DNA, leading to structural modifications that disrupt replication fidelity. The compound's ability to generate reactive oxygen species enhances its mutagenic potential, influencing cellular pathways related to oxidative stress and DNA repair. Its distinct interaction profile makes it a critical agent for exploring genetic mutations and instability. | ||||||
4-IPP | 41270-96-6 | sc-361082 sc-361082A | 10 mg 50 mg | $214.00 $838.00 | 3 | |
4-IPP is a notable mutagenesis research chemical characterized by its ability to engage in nucleophilic substitution reactions. Its structure allows for the formation of covalent bonds with biomolecules, particularly targeting DNA bases. This interaction can induce point mutations and chromosomal aberrations, thereby altering genetic stability. Additionally, 4-IPP's reactivity with cellular components can trigger signaling pathways associated with stress responses, making it a valuable tool for studying mutagenic mechanisms. | ||||||
Quercetin 3-β-D-glucoside | 21637-25-2 | sc-229029 | 10 mg | $35.00 | ||
Quercetin 3-β-D-glucoside is a flavonoid glycoside that exhibits unique interactions with cellular macromolecules, particularly through its capacity to form hydrogen bonds and π-π stacking with nucleic acids. This compound can influence gene expression by modulating transcription factors, potentially leading to alterations in cellular pathways. Its antioxidant properties may also play a role in mitigating oxidative stress, providing insights into mutagenesis and genomic integrity. | ||||||
2-hydroxy Estradiol | 362-05-0 | sc-205085 sc-205085-CW sc-205085A sc-205085B sc-205085C | 1 mg 1 mg 5 mg 10 mg 25 mg | $96.00 $132.00 $353.00 $598.00 $1189.00 | ||
2-Hydroxy Estradiol is a potent estrogen metabolite that engages in specific interactions with estrogen receptors, influencing gene transcription and cellular signaling pathways. Its unique hydroxyl group enhances its reactivity, allowing it to participate in redox reactions and form adducts with DNA, which may lead to mutagenic effects. Additionally, its ability to modulate oxidative stress responses provides a critical perspective on its role in genomic stability and mutagenesis research. | ||||||
N-Nitrosodiethylamine | 55-18-5 | sc-257861 sc-257861A | 5 ml 25 ml | $139.00 $369.00 | 1 | |
N-Nitrosodiethylamine is a potent alkylating agent known for its ability to induce mutations through direct interaction with DNA. Its unique structure facilitates the formation of reactive intermediates that can covalently bind to nucleophilic sites on DNA, leading to mispairing during replication. This compound's reactivity is influenced by environmental factors, which can alter its kinetics and pathways of activation, making it a significant focus in mutagenesis research. | ||||||