4-IPP CAS: 41270-96-6
MF: C10H7IN2
MW: 282.08
An inhibitor of macrophage migration inhibitor factor.

4-IPP (CAS 41270-96-6)

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Synonym: 4-Iodo-6-phenylpyrimidine; MIF Antagonist III
Application: An inhibitor of macrophage migration inhibitor factor
CAS Number: 41270-96-6
Molecular Weight: 282.08
Molecular Formula: C10H7IN2
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4-IPP is an inhibitor of macrophage migration inhibitor factor (MIF). The mode of action relies on the inactivation of biological and catalytic MIF functions. In human lung adenocarcinoma cell lines, 4-IPP has been shown to inhibit independent migration and anchorage in vitro.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (50 mM).
Storage :
Store at 4° C
IC50 :
MIF: IC50 = 4.5 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
817368
MDL Number :
MFCD00234609
SMILES :
C1=CC=C(C=C1)C2=CC(=NC=N2)I

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4-IPP  Product Citations

See how others have used 4-IPP. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26453918  Dickerhof, N. et al. 2015. Free Radic. Biol. Med. 89: 498-511.

Citations 1 to 1 of 1 total
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