2′-Deoxyuridine 5′-monophosphate disodium salt (CAS 42155-08-8)

2′-Deoxyuridine 5′-monophosphate disodium salt is a nucleotide derivative pivotal in the field of molecular biology and genetic research. As a disodium salt, it enhances solubility, facilitating its incorporation into experimental setups. In molecular pathways, it serves as a building block for DNA synthesis, particularly in studies focusing on DNA replication and repair mechanisms. By mimicking the natural substrates of nucleic acid polymerases, this compound allows researchers to investigate the intricacies of enzyme specificity, fidelity, and the effects of mutations on DNA polymerase activity. It is instrumental in the development of novel techniques for DNA sequencing, amplification, and the synthesis of modified nucleic acids, providing insights into gene expression and regulatory mechanisms. Its role extends to the exploration of nucleic acid-protein interactions, aiding in the elucidation of the fundamental processes that govern cellular function and genetic information flow.