Date published: 2025-11-28

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MRP-S21 Activators

The chemical class designated as MRP-S21 Activators comprises a specialized group of compounds identified for their capability to modulate the activity of the MRP-S21 gene. MRP-S21, or Mitochondrial Ribosomal Protein S21, is a gene encoding a protein that forms a component of the small subunit of the mitochondrial ribosome. The mitochondrial ribosome is responsible for synthesizing proteins essential for mitochondrial function and energy production. While the precise function of MRP-S21 is not fully elucidated, it is known to be crucial for mitochondrial protein synthesis and mitochondrial function. Activators of MRP-S21 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.

Characterizing compounds as MRP-S21 Activators usually involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the MRP-S21 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for MRP-S21 gene expression, or modulating post-translational modifications of the MRP-S21 protein. Understanding the molecular mechanisms underlying MRP-S21 activation by these compounds is crucial for elucidating the roles of MRP-S21 in mitochondrial function and cellular metabolism. Further research into MRP-S21 Activators may provide insights into novel cellular pathways involved in mitochondrial biology and contribute to a deeper understanding of MRP-S21's function in maintaining cellular homeostasis.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol can enhance mitochondrial biogenesis through the activation of SIRT1 and PGC-1alpha, potentially upregulating MRPS21 expression as part of the process.

Metformin

657-24-9sc-507370
10 mg
$77.00
2
(0)

Metformin can activate AMPK, which may boost mitochondrial biogenesis and, as a result, theoretically upregulate MRPS21 expression.

β-Nicotinamide mononucleotide

1094-61-7sc-212376
sc-212376A
sc-212376B
sc-212376C
sc-212376D
25 mg
100 mg
1 g
2 g
5 g
$92.00
$269.00
$337.00
$510.00
$969.00
4
(1)

NMN enhances NAD+ biosynthesis, which may stimulate SIRT1, thereby potentially upregulating genes related to mitochondrial function including MRPS21.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$54.00
$123.00
13
(1)

As a PPAR-gamma agonist, pioglitazone can influence mitochondrial biogenesis and may indirectly increase MRPS21 expression.

Bezafibrate

41859-67-0sc-204650B
sc-204650
sc-204650A
sc-204650C
500 mg
1 g
5 g
10 g
$30.00
$45.00
$120.00
$200.00
5
(1)

Bezafibrate activates PPARs, which can promote mitochondrial biogenesis and potentially upregulate MRPS21 expression.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$60.00
$270.00
$350.00
48
(2)

AICAR activates AMPK leading to enhanced mitochondrial biogenesis and possibly the expression of mitochondrial ribosomal proteins like MRPS21.

L-Leucine

61-90-5sc-364173
sc-364173A
25 g
100 g
$21.00
$61.00
(0)

Leucine can stimulate mTOR, which is involved in protein synthesis and may indirectly enhance the synthesis of mitochondrial proteins including MRPS21.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Berberine activates AMPK and can induce mitochondrial biogenesis, which could theoretically upregulate MRPS21 expression.

Pyrroloquinoline quinone

72909-34-3sc-210178
1 mg
$238.00
(1)

PQQ can modulate signaling pathways related to mitochondrial biogenesis, which may influence MRPS21 expression.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

Caffeine can influence AMPK and mTOR signaling pathways, potentially affecting mitochondrial protein synthesis and MRPS21 expression.