The chemical class designated as MRP-S21 Activators comprises a specialized group of compounds identified for their capability to modulate the activity of the MRP-S21 gene. MRP-S21, or Mitochondrial Ribosomal Protein S21, is a gene encoding a protein that forms a component of the small subunit of the mitochondrial ribosome. The mitochondrial ribosome is responsible for synthesizing proteins essential for mitochondrial function and energy production. While the precise function of MRP-S21 is not fully elucidated, it is known to be crucial for mitochondrial protein synthesis and mitochondrial function. Activators of MRP-S21 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.
Characterizing compounds as MRP-S21 Activators usually involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the MRP-S21 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for MRP-S21 gene expression, or modulating post-translational modifications of the MRP-S21 protein. Understanding the molecular mechanisms underlying MRP-S21 activation by these compounds is crucial for elucidating the roles of MRP-S21 in mitochondrial function and cellular metabolism. Further research into MRP-S21 Activators may provide insights into novel cellular pathways involved in mitochondrial biology and contribute to a deeper understanding of MRP-S21's function in maintaining cellular homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol can enhance mitochondrial biogenesis through the activation of SIRT1 and PGC-1alpha, potentially upregulating MRPS21 expression as part of the process. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin can activate AMPK, which may boost mitochondrial biogenesis and, as a result, theoretically upregulate MRPS21 expression. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
NMN enhances NAD+ biosynthesis, which may stimulate SIRT1, thereby potentially upregulating genes related to mitochondrial function including MRPS21. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
As a PPAR-gamma agonist, pioglitazone can influence mitochondrial biogenesis and may indirectly increase MRPS21 expression. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Bezafibrate activates PPARs, which can promote mitochondrial biogenesis and potentially upregulate MRPS21 expression. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMPK leading to enhanced mitochondrial biogenesis and possibly the expression of mitochondrial ribosomal proteins like MRPS21. | ||||||
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $61.00 | ||
Leucine can stimulate mTOR, which is involved in protein synthesis and may indirectly enhance the synthesis of mitochondrial proteins including MRPS21. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine activates AMPK and can induce mitochondrial biogenesis, which could theoretically upregulate MRPS21 expression. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
PQQ can modulate signaling pathways related to mitochondrial biogenesis, which may influence MRPS21 expression. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine can influence AMPK and mTOR signaling pathways, potentially affecting mitochondrial protein synthesis and MRPS21 expression. | ||||||