Date published: 2026-5-3

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mPRγ Activators

mPRγ Activators belong to a distinctive chemical class that primarily interacts with a specific molecular target, the membrane progesterone receptor gamma (mPRγ). These compounds are characterized by their ability to modulate the activity of mPRγ, a member of the membrane progesterone receptor (mPR) family. Unlike classical nuclear progesterone receptors, which primarily mediate genomic effects, mPRγ is localized on the cell membrane and plays a role in non-genomic signaling pathways. As such, mPRγ Activators are unique in their mechanism of action compared to traditional steroid hormones.

The chemical structure of mPRγ Activators varies widely, as they can be synthesized using various organic chemistry techniques. These molecules are designed to bind specifically to the mPRγ receptor, initiating a cascade of intracellular events. Upon activation, mPRγ can initiate rapid cellular responses, such as changes in ion channel activity, intracellular calcium signaling, and activation of various kinases. These non-genomic effects can have profound impacts on cellular physiology, including cell growth, migration, and differentiation.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$52.00
$298.00
3
(1)

Binds to mPRγ receptor and activates gene expression.

Levonorgestrel

797-63-7sc-205731
sc-205731A
100 mg
500 mg
$44.00
$198.00
1
(0)

Activates mPRγ receptor, leading to gene transcription.

Medroxyprogesterone

520-85-4sc-250297
100 mg
$103.00
(0)

Binds to mPRγ, modulating gene expression pathways.

Norethindrone

68-22-4sc-204822
sc-204822B
sc-204822A
sc-204822C
250 mg
500 mg
1 g
5 g
$39.00
$70.00
$128.00
$507.00
(1)

Acts as a ligand for mPRγ, triggering gene activation.

Dienogest

65928-58-7sc-211310
10 mg
$180.00
1
(1)

Modulates mPRγ receptor, leading to gene expression.

Drospirenone

67392-87-4sc-218277
10 mg
$209.00
(0)

Activates mPRγ, leading to altered gene expression.

Ethisterone

434-03-7sc-204746
sc-204746A
1 g
5 g
$40.00
$78.00
(0)

Binds to mPRγ and influences gene transcription.

Desogestrel

54024-22-5sc-211274
10 mg
$300.00
(0)

Acts as an mPRγ agonist, influencing gene expression.