Date published: 2025-9-26

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Desogestrel (CAS 54024-22-5)

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Application:
Desogestrel is a progestogen that has low androgenic potency
CAS Number:
54024-22-5
Purity:
≥98%
Molecular Weight:
310.47
Molecular Formula:
C22H30O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Desogestrel is a compound of interest in the field of biochemistry and endocrinology, where it is the subject of research on its interactions with various steroid hormone receptors. Its structure allows for the binding to progesterone receptors, and studies often explore its affinity and selectivity for these receptors in various tissues. Research on Desogestrel also involves investigating its metabolism and the subsequent formation of active metabolites, which are important for understanding its biological effects on a molecular level. Additionally, Desogestrel′s role in the regulation of gene expression is a key area of investigation, particularly in relation to proteins involved in reproductive processes. The compound is frequently used as a reference in studies examining the biological activities of synthetic progestins. Moreover, researchers are interested in its effects on lipid metabolism and how it influences the synthesis and breakdown of different lipid molecules within cells.


Desogestrel (CAS 54024-22-5) References

  1. The new era in oral contraception: pills containing gestodene, norgestimate, and desogestrel.  |  London, RS. 1992. Obstet Gynecol Surv. 47: 777-82. PMID: 1436906
  2. Drug safety evaluation of desogestrel.  |  Scala, C., et al. 2013. Expert Opin Drug Saf. 12: 433-44. PMID: 23560561
  3. Pharmacokinetic evaluation of desogestrel as a female contraceptive.  |  Grandi, G., et al. 2014. Expert Opin Drug Metab Toxicol. 10: 1-10. PMID: 24102478
  4. Oral Desogestrel as Endometrial Preparation before Operative Hysteroscopy: A Systematic Review.  |  Ciebiera, M., et al. 2021. Gynecol Obstet Invest. 86: 209-217. PMID: 33951627
  5. Twelve years of clinical experience with an oral contraceptive containing 30 micrograms ethinyloestradiol and 150 micrograms desogestrel.  |  Fotherby, K. 1995. Contraception. 51: 3-12. PMID: 7750281
  6. Progestins in preventive hormone therapy. Including pharmacology of the new progestins, desogestrel, norgestimate, and gestodene: are there advantages?  |  Sobel, NB. 1994. Obstet Gynecol Clin North Am. 21: 299-319. PMID: 7936546
  7. Clinical and metabolic features of desogestrel: a new oral contraceptive preparation.  |  Archer, DF. 1994. Am J Obstet Gynecol. 170: 1550-5. PMID: 8178905
  8. Selectivity information on desogestrel.  |  Collins, D. 1993. Am J Obstet Gynecol. 168: 1010-6. PMID: 8447353
  9. Contraceptive efficacy of a monophasic oral contraceptive containing desogestrel.  |  Corson, SL. 1993. Am J Obstet Gynecol. 168: 1017-20. PMID: 8447354
  10. Lipid metabolism effects with desogestrel-containing oral contraceptives.  |  Burkman, RT. 1993. Am J Obstet Gynecol. 168: 1033-40. PMID: 8447357
  11. Effects of desogestrel on carbohydrate metabolism.  |  Shoupe, D. 1993. Am J Obstet Gynecol. 168: 1041-7. PMID: 8447358
  12. Desogestrel, norgestimate, and gestodene: the newer progestins.  |  Kaplan, B. 1995. Ann Pharmacother. 29: 736-42. PMID: 8520092
  13. Desogestrel.  |  Stone, SC. 1995. Clin Obstet Gynecol. 38: 821-8. PMID: 8616978
  14. Pharmacokinetics of the new progestogens and influence of gestodene and desogestrel on ethinylestradiol metabolism.  |  Stanczyk, FZ. 1997. Contraception. 55: 273-82. PMID: 9220223

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Desogestrel, 10 mg

sc-211274
10 mg
$300.00