MOSPD3 Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a specific inhibitor of phosphoinositide 3-kinases (PI3K), which play a key role in various signaling pathways, including those regulating membrane trafficking. MOSPD3, a membrane-associated protein, may rely on PI3K-dependent trafficking to function properly. Thus, LY294002 can indirectly reduce MOSPD3 activity by hindering its transport to the membrane. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor that can indirectly affect MOSPD3 by downregulating cellular processes such as protein synthesis and trafficking, which are crucial for the maintenance of membrane proteins. By inhibiting mTOR, Rapamycin may decrease the overall expression and membrane localization of MOSPD3. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is another potent and irreversible inhibitor of PI3K. Similar to LY294002, Wortmannin can disrupt the PI3K pathway, which is essential for membrane dynamics and protein trafficking. This disruption can indirectly lead to reduced MOSPD3 activity by affecting its membrane association. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynasore is a GTPase inhibitor that targets dynamin, a protein involved in endocytosis and vesicle trafficking. By inhibiting dynamin, Dynasore can affect the endocytic recycling of membrane proteins like MOSPD3, leading to decreased functional activity at the cell surface. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A is an inhibitor of ADP-ribosylation factor (ARF), a small GTPase involved in the formation of the coat protein complex I (COPI) vesicle. By disrupting vesicular transport, Brefeldin A can indirectly inhibit the trafficking of MOSPD3 to the membrane. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D disrupts the actin cytoskeleton, which is crucial for various cellular processes, including vesicle movement and membrane dynamics. By destabilizing actin filaments, Cytochalasin D can indirectly inhibit MOSPD3's association with the membrane. | ||||||
Gö 6976 | 136194-77-9 | sc-221684 | 500 µg | $227.00 | 8 | |
Gö6976 is a potent inhibitor of certain protein kinase C (PKC) isoenzymes. PKC is involved in signaling pathways that regulate cellular adhesion and movement, which could affect the localization and function of MOSPD3. By inhibiting PKC, Gö6976 may reduce the surface expression of MOSPD3. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a selective inhibitor of mitogen-activated protein kinase kinase (MEK), which is part of the MAPK/ERK pathway. The MAPK/ERK pathway is involved in cell proliferation and differentiation, which can influence the expression and functionality of MOSPD3. By inhibiting MEK, PD98059 may indirectly decrease MOSPD3 activity. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $203.00 $469.00 $1509.00 | 1 | |
NF449 is a potent and selective antagonist of G-protein coupled receptor P2X1, which is involved in ATP-mediated cellular signaling. Given that GPCRs can influence various cellular functions, including the trafficking of proteins like MOSPD3, NF449 could indirectly inhibit the functional activity of MOSPD3 by modulating GPCR signaling. | ||||||
Endothall | 145-73-3 | sc-201325 sc-201325A | 20 mg 100 mg | $49.00 $203.00 | 1 | |
Endothall is an inhibitor that can disrupt ATPase activity. As MOSPD3 is a membrane protein, it may rely on ATP-driven processes for its proper function and localization. By inhibiting ATPases, Endothall can indirectly affect the activity of MOSPD3. | ||||||