MORG1 activators refer to compounds or molecules that influence the activity or function of the protein known as MORG1, which stands for Mitogen-Regulated GRB2-Associated Binding Protein 1. MORG1 is a key signaling protein that plays a pivotal role in various cellular processes, particularly in the regulation of cell growth, differentiation, and survival. Understanding the role of MORG1 and its activation is essential for unraveling the complexities of cellular signaling pathways.
MORG1 acts as an adaptor protein, meaning it facilitates the interaction between other signaling molecules within the cell. One of its significant roles is in the activation of the mitogen-activated protein kinase (MAPK) signaling pathway, which is involved in transmitting extracellular signals to the cell nucleus, ultimately leading to changes in gene expression. By serving as a scaffold protein, MORG1 helps assemble signaling complexes that allow for efficient signal transduction. Activators of MORG1 may influence its binding to specific partners, modulating the strength or duration of signaling cascades downstream, and impacting various cellular responses. Research into MORG1 activators can provide valuable insights into the regulation of critical cellular pathways that control cell growth, differentiation, and survival. Understanding the intricate mechanisms by which MORG1 interacts with other proteins and how its activity can be modulated may have implications in fields such as cell biology and cancer research, where dysregulated signaling pathways can lead to pathological conditions. Studying MORG1 activators is part of the broader effort to decipher the complex web of intracellular signaling and its relevance to cellular physiology and disease.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can regulate gene expression through retinoic acid receptors, potentially affecting MORG1 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound can inhibit DNA methylation, potentially leading to the activation of MORG1 gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As a histone deacetylase inhibitor, it may increase histone acetylation and potentially upregulate MORG1 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By increasing cAMP levels, Forskolin can activate PKA, which may influence transcription factors that regulate MORG1. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
This HDAC inhibitor can cause chromatin remodeling, potentially leading to increased expression of MORG1. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide induces DNA damage response, which could lead to the activation of repair genes including MORG1. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium affects GSK-3 activity and Wnt signaling, which might influence the expression of MORG1. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
This glucocorticoid can modulate gene expression through its receptor, potentially affecting MORG1 levels. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
As an MEK inhibitor, PD98059 can affect the MAPK pathway, which may play a role in MORG1 expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
This JNK inhibitor can alter stress response pathways, potentially impacting the expression of MORG1. | ||||||