MORG1 Inhibitors
MORG1 inhibitors are a class of chemical compounds designed to interact with and modulate the activity of the MORG1 protein within biological systems. MORG1, also known as MAPK organizer 1, is a multifunctional protein that serves as a scaffold in various cellular signaling pathways, particularly those involving the Mitogen-Activated Protein Kinase (MAPK) cascade. Its primary role lies in facilitating the assembly of protein complexes and promoting efficient signal transduction from cell surface receptors to downstream intracellular effectors. MORG1 inhibitors are developed to selectively target MORG1, either by binding directly to the protein or by interfering with its scaffold functions, with the goal of regulating specific cellular processes related to signal transduction and cellular responses.
The study of MORG1 inhibitors stems from the fundamental importance of MORG1 in orchestrating cellular signaling events. The MAPK pathway, in which MORG1 plays a vital role, regulates various cellular processes, including proliferation, differentiation, and stress responses. By modulating the activity of MORG1, these inhibitors offer a means to investigate the intricate molecular mechanisms underlying signal transduction and cellular communication.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, a central regulator of cell growth and metabolism. Given the interconnectedness of signaling pathways, mTOR inhibition might indirectly affect MORG1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
This compound inhibits PI3K, which can impact downstream signaling pathways that might cross-talk with MAPK pathways and influence MORG1. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor which, by modulating the PI3K/AKT pathway, could indirectly influence MORG1's role or expression. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
As a proteasome inhibitor, bortezomib can affect protein turnover and might indirectly influence MORG1 stability or expression. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
By inhibiting glycolysis, 2-deoxyglucose can influence cellular energy status and potentially modulate signaling pathways that impact MORG1. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
Metformin impacts cellular metabolism and AMPK signaling, which could indirectly affect MORG1 expression or activity. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
This compound interferes with nucleotide synthesis and can influence cell proliferation and signaling, potentially affecting MORG1. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Imatinib targets specific kinases, and its broad effects on kinase signaling might indirectly influence MORG1. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $153.00 | 5 | |
This compound inhibits Bruton's tyrosine kinase (BTK) and might influence signaling pathways related or parallel to MORG1's function. | ||||||
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 | 612847-09-3 | sc-202048 sc-202048A | 1 mg 5 mg | $204.00 $265.00 | 29 | |
By inhibiting Akt, this compound could modulate signaling pathways that might cross-talk with those involving MORG1. | ||||||