MOG Activators
MOG activators, in a broad sense, encompass a range of compounds that can indirectly influence the expression or function of MOG through various biochemical and cellular pathways. These activators may function by promoting the differentiation and maturation of oligodendrocytes, the cells responsible for the formation of the myelin sheath, which contains MOG. Hormones like thyroid hormones and compounds like retinoic acid and vitamin D3 are known to have a role in CNS development and myelination, and thus could contribute to higher MOG expression or stability in the myelin membrane.
Additionally, compounds that modulate immune function within the CNS could also be considered as indirect activators of MOG. This can include agents that have immunomodulatory effects, such as glucocorticoids or sphingosine-1-phosphate receptor modulators, which could lead to an environment that supports the integrity of the myelin sheath and possibly the function of MOG.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $40.00 $75.00 $150.00 | ||
Thyroid hormone that can enhance oligodendrocyte differentiation, potentially increasing the expression of MOG in the myelin. | ||||||
L-Thyroxine, free acid | 51-48-9 | sc-207813 sc-207813A | 100 mg 500 mg | $34.00 $73.00 | 2 | |
Thyroid hormone involved in CNS development and myelination, which may indirectly affect MOG expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences gene expression and could promote oligodendrocyte maturation, possibly leading to increased MOG expression. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Regulates immune function and has been implicated in CNS myelination, potentially influencing MOG activity. | ||||||
Clobetasol Propionate | 25122-46-7 | sc-204692 sc-204692A | 100 mg 500 mg | $51.00 $157.00 | 1 | |
Glucocorticoid that may enhance oligodendrocyte precursor cell differentiation, potentially affecting MOG expression. | ||||||
Fluoxetine | 54910-89-3 | sc-279166 | 500 mg | $312.00 | 9 | |
Has been shown to promote myelin repair, potentially increasing MOG expression through improved oligodendrocyte function. | ||||||
Benztropine mesylate | 132-17-2 | sc-202495 sc-202495A | 1 g 5 g | $45.00 $157.00 | 3 | |
Antimuscarinic agent that has been found to promote remyelination, which could indirectly affect MOG expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences neuroprotective pathways and could indirectly support oligodendrocyte health and MOG expression. | ||||||
Muscimol | 2763-96-4 | sc-200460 sc-200460A | 5 mg 25 mg | $158.00 $526.00 | 2 | |
GABA agonist that could modulate neuroinflammatory responses in the CNS, potentially influencing MOG activity. | ||||||
FTY720 | 162359-56-0 | sc-202161 sc-202161A sc-202161B | 1 mg 5 mg 25 mg | $32.00 $75.00 $118.00 | 14 | |
Another sphingosine-1-phosphate receptor modulator that has implications for CNS immune function and myelination, affecting MOG. | ||||||