MOBKL2C Activators represent a specialized group of chemical compounds designed to selectively enhance the activity of MOBKL2C, a protein with crucial roles in cellular processes such as cell division and regulation of the cell cycle. MOBKL2C, also known as MOB1B (Mps One Binder Kinase Activator-Like 2C), belongs to the MOB kinase activator family and plays a central role in coordinating mitotic events and ensuring proper cell division. The development of MOBKL2C Activators represents a significant scientific endeavor aimed at understanding and modulating the activity of this protein, shedding light on its functions in cell biology. These activators are synthesized through intricate chemical engineering processes, with the goal of producing molecules that can specifically interact with MOBKL2C, potentially enhancing its function or revealing its natural regulators. The effective design of MOBKL2C Activators necessitates a deep understanding of the protein's structure, its kinase domains, and its potential binding sites.
The study of MOBKL2C Activators encompasses a multidisciplinary research approach, integrating techniques from molecular biology, biochemistry, and cell biology to elucidate how these compounds interact with MOBKL2C. Scientists employ protein expression and purification methods to obtain MOBKL2C for further analysis. Functional assays, including kinase activity assays and cell cycle progression experiments, are used to assess the impact of activators on MOBKL2C-mediated processes crucial for proper cell division. Structural studies, such as X-ray crystallography or computational modeling, play a pivotal role in determining the three-dimensional structure of MOBKL2C, identifying potential activator binding sites, and elucidating the conformational changes associated with activation. Computational modeling and molecular docking further aid in predicting the interactions between MOBKL2C and potential activators, guiding the rational design and optimization of these molecules for increased specificity and efficacy. Through this comprehensive research endeavor, the study of MOBKL2C Activators aims to advance our understanding of cell division and cell cycle regulation, contributing to the broader field of cell biology and cell proliferation research.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin raises intracellular cAMP levels, potentially influencing cell cycle-related gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 inhibits PI3K, altering AKT signaling and possibly affecting cell cycle gene expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, which may impact the expression of genes involved in cell cycle control. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK inhibitor that might modulate the MAPK/ERK pathway, influencing cell proliferation genes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, which can alter transcriptional regulation of cell cycle-associated genes. | ||||||
SB 202190 | 152121-30-7 | sc-202334 sc-202334A sc-202334B | 1 mg 5 mg 25 mg | $30.00 $125.00 $445.00 | 45 | |
SB203580 is a p38 MAPK inhibitor which may affect transcription factors for cell cycle regulation. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an inhibitor of MEK1/2, potentially modulating cell cycle-related gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin modulates multiple cell signaling pathways, possibly influencing cell cycle gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol interacts with various signaling pathways that can impact cell cycle and survival. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, as a HDAC inhibitor, may alter chromatin structure and gene expression profiles. |