MMD2 Activators
MMD2 Activators are a class of chemical compounds that specifically enhance the functional activity of MMD2, a crucial protein involved in the mitochondrial leucine degradation pathway. Several compounds that participate in or influence this process can logically serve as MMD2 activators. For instance, Pyruvate, Acetyl-CoA, and Leucine are compounds that directly participate in the metabolic pathways where MMD2 operates. Pyruvate enhances the Krebs cycle, leading to an increase in Acetyl-CoA, which is a substrate in the leucine degradation pathway, hence enhancing MMD2 activity. Acetyl-CoA directly provides the substrate for the leucine degradation pathway, thus enhancing MMD2 activity, while increased levels of Leucine, being the primary substrate, enhance MMD2 activity byincreasing the rate of the leucine degradation pathway.
Other MMD2 activators, Alpha-Ketoglutarate, Citrate, Oxaloacetate, Coenzyme A (CoA), NADH, Isocitrate, Succinate, Fumarate, and Malate, are compounds that indirectly enhance MMD2 activity by influencing metabolic pathways related to the function of MMD2. Alpha-Ketoglutarate, Citrate, Oxaloacetate, NADH, Isocitrate, Succinate, Fumarate, and Malate all enhance the Krebs cycle, leading to an increase in the production of Acetyl-CoA, which is a substrate in the leucine degradation pathway, potentially leading to enhanced MMD2 activity. CoA, as a central molecule in many metabolic pathways, including the leucine degradation pathway, increases the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA, thus enhancing MMD2 activity.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pyruvic acid | 127-17-3 | sc-208191 sc-208191A | 25 g 100 g | $40.00 $94.00 | ||
Pyruvate is a key intersection in several metabolic pathways. MMD2 is involved in the mitochondrial leucine degradation pathway, where it transforms 3-methylglutaconyl-CoA into 3-hydroxy-3-methylglutaryl-CoA. Pyruvate can enhance the Krebs cycle, leading to an upsurge in the amount of Acetyl-CoA, which is a substrate in the leucine degradation pathway, hence enhancing MMD2 activity. | ||||||
Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $46.00 $80.00 $5712.00 | 3 | |
Acetyl-CoA is directly involved in the leucine degradation pathway, where MMD2 functions. As such, an increased availability of Acetyl-CoA directly provides the necessary substrate for the leucine degradation pathway, thus enhancing MMD2 activity. | ||||||
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $61.00 | ||
Leucine is the primary substrate in the metabolic pathway where MMD2 functions. Enhanced levels of leucine will increase the rate of the leucine degradation pathway, thus enhancing MMD2 activity. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $32.00 $42.00 $62.00 $108.00 $184.00 $724.00 $2050.00 | 2 | |
Alpha-Ketoglutarate is a key component of the Krebs cycle. By enhancing the Krebs cycle, alpha-ketoglutarate can increase the production of Acetyl-CoA, a substrate in the leucine degradation pathway, potentially leading to enhanced MMD2 activity. | ||||||
Citric Acid, Anhydrous | 77-92-9 | sc-211113 sc-211113A sc-211113B sc-211113C sc-211113D | 500 g 1 kg 5 kg 10 kg 25 kg | $49.00 $108.00 $142.00 $243.00 $586.00 | 1 | |
Citrate is a key component of the Krebs cycle. Increased levels of citrate can enhance the Krebs cycle, leading to increased production of Acetyl-CoA, which is a substrate in the leucine degradation pathway, hence enhancing MMD2 activity. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $300.00 $944.00 $7824.00 | 1 | |
Oxaloacetate is a component of the Krebs cycle. By enhancing the Krebs cycle, oxaloacetate can increase the production of Acetyl-CoA, a substrate in the leucine degradation pathway, potentially leading to enhanced MMD2 activity. | ||||||
Coenzyme A | 85-61-0 anhydrous | sc-211123 sc-211123A sc-211123B sc-211123C | 10 mg 25 mg 100 mg 250 mg | $70.00 $116.00 $410.00 $785.00 | 1 | |
CoA is a central molecule in numerous metabolic pathways, including the leucine degradation pathway where MMD2 functions. By increasing the availability of CoA, the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA can be enhanced, leading to increased MMD2 activity. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NADH is involved in energy metabolism and can enhance the Krebs cycle. By enhancing the Krebs cycle, NADH can increase the production of Acetyl-CoA, a substrate in the leucine degradation pathway, leading to enhanced MMD2 activity. | ||||||
Succinic acid | 110-15-6 | sc-212961B sc-212961 sc-212961A | 25 g 500 g 1 kg | $44.00 $74.00 $130.00 | ||
Succinate is a component of the Krebs cycle. By enhancing the Krebs cycle, succinate can increase the production of Acetyl-CoA, a substrate in the leucine degradation pathway, potentially leading to enhanced MMD2 activity. | ||||||
Fumaric acid | 110-17-8 | sc-250031 sc-250031A sc-250031B sc-250031C | 25 g 100 g 500 g 2.5 kg | $42.00 $56.00 $112.00 $224.00 | ||
Fumarate is a component of the Krebs cycle. By enhancing the Krebs cycle, fumarate can increase the production of Acetyl-CoA, a substrate in the leucine degradation pathway, potentially leading to enhanced MMD2 activity. | ||||||