The chemical class Mitofilin Activators comprises compounds that influence mitochondrial function and dynamics, potentially affecting Mitofilin's role in maintaining mitochondrial architecture. Compounds like Metformin and Resveratrol activate pathways (AMPK and SIRT1, respectively) crucial for mitochondrial biogenesis and function, which are closely related to Mitofilin's role in mitochondria. Rapamycin, by inhibiting mTOR, influences autophagy and mitochondrial dynamics, potentially impacting Mitofilin activity. Antioxidants such as N-acetylcysteine and Alpha-lipoic acid modulate oxidative stress and mitochondrial metabolism, which can indirectly affect Mitofilin's function in maintaining mitochondrial integrity.
Other compounds like MitoQ, Bezafibrate, and Coenzyme Q10 target mitochondrial processes directly. MitoQ, as a mitochondria-targeted antioxidant, Bezafibrate as a PPAR agonist, and Coenzyme Q10 in the electron transport chain, all potentially modulate the environment in which Mitofilin operates. Compounds like Dichloroacetate and Nicotinamide mononucleotide (NMN) affect mitochondrial metabolism, which is crucial for Mitofilin's role in mitochondrial architecture. Spermidine, known to induce autophagy, may also influence Mitofilin by modulating mitochondrial turnover and dynamics.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenol that activates SIRT1, influencing mitochondrial function and possibly Mitofilin activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, affects autophagy and mitochondrial dynamics, potentially influencing Mitofilin. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
An antioxidant that modulates oxidative stress, possibly affecting mitochondrial function and Mitofilin activity. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
A mitochondria-targeted antioxidant, could influence mitochondrial dynamics and Mitofilin activity. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
A PPAR agonist, influences mitochondrial biogenesis, potentially affecting Mitofilin. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activates AMPK, influencing energy metabolism and potentially Mitofilin activity. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
An antioxidant that affects mitochondrial metabolism, potentially influencing Mitofilin. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Involved in mitochondrial electron transport, could indirectly influence Mitofilin. | ||||||
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $60.00 $125.00 | 5 | |
Modulates pyruvate dehydrogenase activity, affecting mitochondrial metabolism and potentially Mitofilin. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
A NAD+ precursor, influences mitochondrial function, potentially affecting Mitofilin. |