Date published: 2025-10-10

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Mitofilin Activators

The chemical class Mitofilin Activators comprises compounds that influence mitochondrial function and dynamics, potentially affecting Mitofilin's role in maintaining mitochondrial architecture. Compounds like Metformin and Resveratrol activate pathways (AMPK and SIRT1, respectively) crucial for mitochondrial biogenesis and function, which are closely related to Mitofilin's role in mitochondria. Rapamycin, by inhibiting mTOR, influences autophagy and mitochondrial dynamics, potentially impacting Mitofilin activity. Antioxidants such as N-acetylcysteine and Alpha-lipoic acid modulate oxidative stress and mitochondrial metabolism, which can indirectly affect Mitofilin's function in maintaining mitochondrial integrity.

Other compounds like MitoQ, Bezafibrate, and Coenzyme Q10 target mitochondrial processes directly. MitoQ, as a mitochondria-targeted antioxidant, Bezafibrate as a PPAR agonist, and Coenzyme Q10 in the electron transport chain, all potentially modulate the environment in which Mitofilin operates. Compounds like Dichloroacetate and Nicotinamide mononucleotide (NMN) affect mitochondrial metabolism, which is crucial for Mitofilin's role in mitochondrial architecture. Spermidine, known to induce autophagy, may also influence Mitofilin by modulating mitochondrial turnover and dynamics.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

A polyphenol that activates SIRT1, influencing mitochondrial function and possibly Mitofilin activity.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

An mTOR inhibitor, affects autophagy and mitochondrial dynamics, potentially influencing Mitofilin.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$33.00
$73.00
$265.00
$112.00
34
(1)

An antioxidant that modulates oxidative stress, possibly affecting mitochondrial function and Mitofilin activity.

Mito-Q

444890-41-9sc-507441
5 mg
$284.00
(0)

A mitochondria-targeted antioxidant, could influence mitochondrial dynamics and Mitofilin activity.

Bezafibrate

41859-67-0sc-204650B
sc-204650
sc-204650A
sc-204650C
500 mg
1 g
5 g
10 g
$30.00
$45.00
$120.00
$200.00
5
(1)

A PPAR agonist, influences mitochondrial biogenesis, potentially affecting Mitofilin.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$60.00
$270.00
$350.00
48
(2)

Activates AMPK, influencing energy metabolism and potentially Mitofilin activity.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$68.00
$120.00
$208.00
$373.00
$702.00
3
(1)

An antioxidant that affects mitochondrial metabolism, potentially influencing Mitofilin.

Coenzyme Q10

303-98-0sc-205262
sc-205262A
1 g
5 g
$70.00
$180.00
1
(1)

Involved in mitochondrial electron transport, could indirectly influence Mitofilin.

Dichloroacetic acid

79-43-6sc-214877
sc-214877A
25 g
100 g
$60.00
$125.00
5
(0)

Modulates pyruvate dehydrogenase activity, affecting mitochondrial metabolism and potentially Mitofilin.

β-Nicotinamide mononucleotide

1094-61-7sc-212376
sc-212376A
sc-212376B
sc-212376C
sc-212376D
25 mg
100 mg
1 g
2 g
5 g
$92.00
$269.00
$337.00
$510.00
$969.00
4
(1)

A NAD+ precursor, influences mitochondrial function, potentially affecting Mitofilin.