Mex3a activators constitute a novel class of chemical compounds specifically engineered to enhance the activity of the Mex3a protein. This protein is implicated in a variety of cellular processes, including RNA binding and the regulation of gene expression, which are crucial for cell development and differentiation. The development of Mex3a activators is a complex process that involves identifying compounds capable of binding to Mex3a and modulating its activity in a way that promotes its functional engagement in cellular mechanisms. These activators can be diverse in nature, ranging from small molecules to peptides, each designed to interact with Mex3a at specific domains to facilitate its activation. The specificity of these interactions is paramount to ensure that the activation of Mex3a is both effective and selective, thereby minimizing unintended effects on other cellular pathways.
The research and development pipeline for Mex3a activators involves multiple stages, including the use of computational drug design to identify potential binding sites and the application of high-throughput screening techniques to isolate promising candidates. Further in vitro assays are critical to validate the efficacy and safety of these compounds. Detailed structural analysis, often employing techniques such as cryo-electron microscopy or X-ray crystallography, provides insights into the conformational changes induced by activator binding, which is essential for understanding the mechanism of action. Additionally, structure-activity relationship (SAR) studies are conducted to refine the chemical properties of the activators, optimizing their ability to enhance Mex3a activity effectively. Through such research, Mex3a activators emerge as powerful tools for dissecting the intricacies of cellular regulation and hold promise for novel interventions in diseases where Mex3a's activity is a contributing factor.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
May regulate gene expression during differentiation, potentially increasing Mex3a expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Induces ER stress and could lead to increased Mex3a expression as part of the unfolded protein response. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Another ER stress inducer, which could enhance Mex3a expression during the cellular response to stress. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Could upregulate Mex3a as part of the response to inhibited translation and cell growth. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $106.00 $765.00 | 3 | |
Induces oxidative stress, potentially influencing Mex3a expression as part of a stress response. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known to modulate multiple cellular pathways and could affect Mex3a expression in processes such as inflammation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
An antioxidant that may influence Mex3a expression as part of the cellular adaptation to oxidative stress. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Might modulate Mex3a expression through its role in cell differentiation and proliferation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Could activate cellular detoxification pathways, potentially increasing Mex3a expression as part of this process. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $63.00 $173.00 | 7 | |
Mimics low oxygen conditions, potentially upregulating Mex3a as part of the hypoxic response. | ||||||