MetAP-2 Activators
MetAP-2 activators, as a chemical class, encompass a diverse range of compounds that can indirectly influence the activity of MetAP-2 through various biochemical and cellular pathways. These chemicals do not directly interact with MetAP-2 but modulate cellular processes and signaling pathways that eventually impact the enzyme's function. For instance, compounds like sulforaphane and resveratrol activate oxidative stress response and SIRT1 pathways, respectively. These activations can lead to a cascade of cellular events, ultimately influencing MetAP-2 activity as part of the cell's broader response to these stimuli.
The interaction of these chemicals with cellular pathways demonstrates the interconnected nature of cellular processes. Chemicals like curcumin and epigallocatechin gallate (EGCG) modulate key signaling pathways such as NF-κB and apoptosis-related pathways. This modulation can indirectly affect MetAP-2 activity, given its role in angiogenesis and cell proliferation. Similarly, micronutrients like zinc and selenium are essential for numerous enzymatic processes and antioxidant defense systems. Their adequate levels are crucial for maintaining the normal function of a wide array of enzymes, potentially including MetAP-2.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Induces oxidative stress response pathways. This can lead to the activation of cellular defense mechanisms, potentially influencing MetAP-2 activity indirectly. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Activates SIRT1, which is involved in cell survival pathways. SIRT1 activation can modulate cellular processes that may indirectly enhance MetAP-2 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Influences NF-κB signaling, which is integral to inflammatory response and cell proliferation. This could indirectly affect MetAP-2's role in these processes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Affects multiple signaling pathways, including those related to oxidative stress and apoptosis, which could indirectly modify MetAP-2 activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Modulates various signaling pathways, including those related to cell proliferation and survival, potentially impacting MetAP-2 activity. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Essential for numerous enzymatic processes. Adequate zinc levels are crucial for the normal function of enzymes, potentially including MetAP-2. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
Plays a role in antioxidant defense systems. Its presence is vital for the proper functioning of various cellular processes, possibly affecting MetAP-2. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Involved in cellular growth and immune function. Its pathways might intersect with those involving MetAP-2, indirectly influencing its activity. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
Acts as an antioxidant and a precursor to glutathione, potentially affecting cellular processes related to MetAP-2's function. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Involved in mitochondrial bioenergetics and antioxidant defense, potentially influencing pathways related to MetAP-2. | ||||||