MEGF10 Activators
MEGF10 Activators represent a novel group of chemical compounds designed to modulate the activity of MEGF10, a member of the Multiple EGF-like-domains 10 protein family. MEGF10 itself is known to play a crucial role in various cellular processes, particularly those related to cell adhesion, migration, and signaling. The activators within this class are engineered to enhance the function or expression of MEGF10, thereby influencing its downstream cellular effects. The intricate design of these compounds may involve targeting specific binding sites or regulatory elements associated with MEGF10, ultimately leading to a controlled and heightened activation of this protein.
Researchers and developers are likely exploring MEGF10 Activators for their potential in elucidating the intricate molecular pathways associated with MEGF10-mediated cellular responses. Understanding the precise mechanisms and consequences of MEGF10 activation can provide valuable insights into fundamental biological processes, with implications for various fields such as cell biology and neuroscience. The development and study of MEGF10 Activators may contribute to advancing our understanding of cellular interactions and pave the way for future research avenues in basic science and potentially translational applications.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Chlorpromazine is a dopamine receptor antagonist and can participate in the phosphatidylinositol signaling system, a pathway that MEGF10 is involved in. This chemical can indirectly enhance MEGF10's activity by stimulating the phosphatidylinositol signaling system. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride is a GSK3 inhibitor that can activate the Wnt/β-catenin signaling pathway, indirectly influencing MEGF10. As Wnt/β-catenin signaling is involved in cellular adhesion, it can enhance the phagocytic activity of MEGF10. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, which increases cAMP levels, leading to activation of Protein Kinase A (PKA). PKA phosphorylation events can indirectly influence the activity of MEGF10, enhancing its phagocytic function. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
SB216763 is a potent and selective GSK-3 inhibitor. By inhibiting GSK-3, it can indirectly enhance the activity of MEGF10 in the Wnt/β-catenin signaling pathway, which is associated with cell-cell adhesion and phagocytosis. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a potent and selective MEK inhibitor that can influence the ERK/MAPK signaling pathway. ERK/MAPK signaling can indirectly enhance MEGF10 activity by modulating cellular processes like cell proliferation and differentiation. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a selective Rho-associated protein kinase (ROCK) inhibitor. ROCK inhibition can influence cytoskeleton reorganization, a process that can indirectly enhance MEGF10's role in cell engulfment and phagocytosis. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor. By inhibiting PI3K, it can influence the PI3K/AKT/mTOR pathway, which can indirectly enhance the functional activity of MEGF10 in cell engulfment and phagocytosis. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 is an inhibitor of NF-κB activation. By inhibiting NF-κB, it can influence inflammatory responses, which can indirectly enhance the functional activity of MEGF10 in phagocytosis. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent and selective PI3K inhibitor. By inhibiting PI3K, it can influence the PI3K/AKT/mTOR pathway, which can indirectly enhance the functional activity of MEGF10 in cell engulfment and phagocytosis. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is an inhibitor of histone deacetylase. By modulating histone acetylation, it can influence gene expression that indirectly enhances the functional activity of MEGF10 in phagocytosis. | ||||||