Date published: 2025-11-24

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Med25 Inhibitors

Med25 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the Med25 protein, also known as Mediator complex subunit 25. Med25 is a component of the Mediator complex, a multiprotein complex that plays a crucial role in regulating gene expression by facilitating communication between transcription factors and RNA polymerase II during transcription initiation. The Mediator complex acts as a bridge, connecting transcription factors bound to enhancer regions of genes with the transcriptional machinery at the promoter regions, ultimately ensuring the proper initiation of transcription. Med25, in particular, is associated with specific transcriptional activators and coactivators, influencing the expression of genes involved in various cellular processes, including development, differentiation, and homeostasis. Inhibitors of Med25 are primarily developed for research purposes, serving as essential tools for scientists and researchers to investigate the molecular mechanisms and functions associated with this protein in the context of transcriptional regulation and cellular biology. Med25 inhibitors are typically composed of small molecules or chemical compounds specifically designed to interact with the Med25 protein, disrupting its normal function as a mediator of transcriptional activation. By inhibiting Med25, these compounds can potentially interfere with the recruitment of transcriptional activators to target genes, leading to alterations in gene expression patterns and cellular responses. Researchers use Med25 inhibitors in laboratory settings to manipulate the activity of this protein and study its roles in various cellular processes, including those related to development and differentiation. These inhibitors provide valuable insights into the molecular mechanisms by which Med25 influences transcriptional regulation and contribute to a deeper understanding of its significance in the context of cellular biology. While Med25 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of Med25-mediated transcriptional activation and its impact on gene expression.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

A diterpene triepoxide that may downregulate transcription factors, potentially leading to reduced Med25 expression.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

An aureolic acid that binds to GC-rich DNA sequences, possibly affecting the transcription of genes including Med25.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

A compound that intercalates DNA and inhibits RNA polymerase, which could reduce Med25 mRNA synthesis.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A nucleoside analog that inhibits DNA methyltransferase, potentially affecting Med25 gene expression epigenetically.

RGFP966

1357389-11-7sc-507300
5 mg
$115.00
(0)

A selective HDAC3 inhibitor that might alter chromatin accessibility and impact Med25 expression.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

A flavonoid that may modulate various signaling pathways and transcription factors, potentially influencing Med25 expression.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

A compoundthat can alkalize lysosomes and interfere with cellular processes, possibly affecting Med25 expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

A short-chain fatty acid that acts as an HDAC inhibitor, potentially leading to changes in Med25 gene expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

An mTOR inhibitor which could affect transcription factor activity and potentially downregulate Med25 expression.

Pyrvinium Pamoate

3546-41-6sc-476920A
sc-476920
250 mg
500 mg
$224.00
$414.00
(0)

An anthelmintic agent that can affect Wnt signaling, which may indirectly influence Med25 expression.