Date published: 2026-3-28

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MDR Antibodies

Santa Cruz Biotechnology features a diverse variety of MDR Antibodies targeting multidrug resistance proteins. MDR Antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Multidrug resistance proteins facilitate the transport of drugs and other substances across cellular membranes, significantly impacting the efficacy of chemotherapy and other therapeutic interventions. Understanding MDR protein function and regulation is essential for developing strategies to overcome drug resistance in cancer treatment. The study of multidrug resistance proteins continues to advance personalized medicine and improve patient outcomes. MDR protein research has revealed crucial insights into cellular defense mechanisms and therapeutic resistance patterns. Ongoing investigations of MDR proteins help identify novel therapeutic targets and potential drug resistance markers. Research utilizing Santa Cruz Biotechnology monoclonal antibodies contributes to advancing cancer treatment strategies and improving therapeutic outcomes worldwide.

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MDR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MDR1/ABCB1 Antibody (D-11)

sc-55510mouse IgG2b κ1040-1280 (h)WB, IP, IF, IHC(P), ELISAm, r, h
187
(33)

MDR1/ABCB1 Antibody (G-1)

sc-13131mouse IgG2b κ1040-1280 (h)WB, IP, IF, IHC(P), ELISAh
115
(11)

MDR1/ABCB1 Antibody (UIC2)

sc-73354mouse IgG2a κFL (h)IP, IF, IHC(P), FCMh
31
(3)

MDR3/ABCB4 Antibody (P3-II-26)

sc-551480mouse IgG2b629-692 (h)WB, IP, IF, FCMh

new

(0)

MDR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MDR1/ABCB1 CRISPR/Cas9 KO Plasmid (h)

sc-400178hGene KnockoutGFP0
(0)

MDR1/ABCB1 HDR Plasmid (h)

sc-400178-HDRhHomology Directed RepairPuromycin0
(0)

MDR1/ABCB1 Double Nickase Plasmid (h)

sc-400178-NIChGene KnockoutPuromycin0
(0)

MDR1/ABCB1 Double Nickase Plasmid (h2)

sc-400178-NIC-2hGene KnockoutPuromycin0
(0)

MDR1/ABCB1 CRISPR/Cas9 KO Plasmid (m)

sc-422215mGene KnockoutGFP0
(0)

MDR1/ABCB1 HDR Plasmid (m)

sc-422215-HDRmHomology Directed RepairPuromycin0
(0)

MDR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MDR1/ABCB1 CRISPR Activation Plasmid (h)

sc-400178-ACThGene ActivationPuro, Blast, Hygro0
(0)

MDR1/ABCB1 CRISPR Activation Plasmid (h2)

sc-400178-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MDR1/ABCB1 Lentiviral Activation Particles (h)

sc-400178-LAChGene ActivationPuro, Blast, Hygro0
(0)

MDR1/ABCB1 Lentiviral Activation Particles (h2)

sc-400178-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MDR1/ABCB1 CRISPR Activation Plasmid (m)

sc-422215-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MDR1/ABCB1 CRISPR Activation Plasmid (m2)

sc-422215-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MDR3/ABCB4 CRISPR Activation Plasmid (h)

sc-404167-ACThGene ActivationPuro, Blast, Hygro0
(0)

MDR3/ABCB4 Lentiviral Activation Particles (h)

sc-404167-LAChGene ActivationPuro, Blast, Hygro0
(0)

MDR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MDR1/ABCB1 siRNA (h)

sc-29395hGene SilencingN/A
21
(2)

MDR1/ABCB1 shRNA Plasmid (h)

sc-29395-SHhGene SilencingPuromycin
21
(2)

MDR1/ABCB1 shRNA (h) Lentiviral Particles

sc-29395-VhGene SilencingPuromycin
21
(2)

MDR1/ABCB1 siRNA (m)

sc-35891mGene SilencingN/A
6
(0)

MDR1/ABCB1 shRNA Plasmid (m)

sc-35891-SHmGene SilencingPuromycin
6
(0)

MDR1/ABCB1 shRNA (m) Lentiviral Particles

sc-35891-VmGene SilencingPuromycin
6
(0)

MDR2/ABCB4 siRNA (m)

sc-37016mGene SilencingN/A0
(0)

MDR2/ABCB4 shRNA Plasmid (m)

sc-37016-SHmGene SilencingPuromycin0
(0)

MDR2/ABCB4 shRNA (m) Lentiviral Particles

sc-37016-VmGene SilencingPuromycin0
(0)

MDR3/ABCB4 siRNA (h)

sc-37015hGene SilencingN/A
1
(0)

MDR3/ABCB4 shRNA Plasmid (h)

sc-37015-SHhGene SilencingPuromycin
1
(0)

MDR3/ABCB4 shRNA (h) Lentiviral Particles

sc-37015-VhGene SilencingPuromycin
1
(0)

MDR3/ABCB4 siRNA (m)

sc-37017mGene SilencingN/A0
(0)

MDR3/ABCB4 shRNA Plasmid (m)

sc-37017-SHmGene SilencingPuromycin0
(0)

MDR3/ABCB4 shRNA (m) Lentiviral Particles

sc-37017-VmGene SilencingPuromycin0
(0)