Date published: 2026-1-16

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Mcl-1 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Mcl-1 monoclonal antibodies for research in understanding cellular processes. Mcl-1 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Mcl-1, a member of the Bcl-2 family of proteins, plays a critical role in regulating apoptosis and cell survival. Expression of Mcl-1 is often associated with cancer progression, making it a significant target for therapeutic intervention. Understanding Mcl-1 function is essential for elucidating mechanisms of resistance to chemotherapy and developing novel cancer treatments. Mcl-1 monoclonal antibodies enable researchers to explore cellular pathways involved in survival and death mechanisms. Research utilizing Mcl-1 monoclonal antibodies contributes to understanding protein interactions and regulatory networks in cancer biology. Investigating Mcl-1 expression patterns helps identify potential therapeutic targets in various cancer types. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing cancer research and therapeutic development.

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Mcl-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Mcl-1 Antibody (22)

sc-12756mouse IgG1 κFL (h)WB, IP, ELISAh
164
(28)

Mcl-1 Antibody (B-6)

sc-74436mouse IgG2a κ1-260 (h)WB, IP, IF, ELISAm, r, h
9
(7)

Mcl-1 Antibody (RC13)

sc-56152mouse IgG1 κ1-327 (h)WB, IP, IF, IHC(P)h > m, r
11
(6)

Mcl-1 Antibody (G-7)

sc-74437mouse IgG2a κ1-260 (h)WB, IP, IF, IHC(P), ELISAm, r, h
14
(12)

Mcl-1 Antibody (C-2)

sc-377487mouse IgM κ111-149 (h)WB, IP, IF, IHC(P), ELISAm, r, h
8
(6)

Mcl-1 Antibody (MCL-401)

sc-69839mouse IgG1FL (h)WB, IP, IF, ELISAh
3
(4)

Mcl-1 Antibody (MCL-2601)

sc-69840mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(2)

Mcl-1 Antibody (MCL701)

sc-69838mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAh
1
(4)

Mcl-1 Antibody (8C6D4B1)

sc-53951mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
5
(1)

Mcl-1 Antibody (RC31)

sc-53971mouse IgG1 κ1-327 (h)WB, IP, IFh

new

(2)

Mcl-1 Antibody (MCL-1801)

sc-69841mouse IgG1FL (h)WB, IP, IF, ELISAh
2
(1)

Mcl-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Mcl-1 CRISPR/Cas9 KO Plasmid (h)

sc-400079hGene KnockoutGFP
5
(0)

Mcl-1 HDR Plasmid (h)

sc-400079-HDRhHomology Directed RepairPuromycin
5
(0)

Mcl-1 Double Nickase Plasmid (h)

sc-400079-NIChGene KnockoutPuromycin
5
(0)

Mcl-1 Double Nickase Plasmid (h2)

sc-400079-NIC-2hGene KnockoutPuromycin
5
(0)

Mcl-1 CRISPR/Cas9 KO Plasmid (m)

sc-421589mGene KnockoutGFP0
(0)

Mcl-1 HDR Plasmid (m)

sc-421589-HDRmHomology Directed RepairPuromycin0
(0)

Mcl-1 Double Nickase Plasmid (m)

sc-421589-NICmGene KnockoutPuromycin0
(0)

Mcl-1 Double Nickase Plasmid (m2)

sc-421589-NIC-2mGene KnockoutPuromycin0
(0)

Mcl-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Mcl-1 CRISPR Activation Plasmid (h)

sc-400079-ACThGene ActivationPuro, Blast, Hygro
5
(0)

Mcl-1 CRISPR Activation Plasmid (h2)

sc-400079-ACT-2hGene ActivationPuro, Blast, Hygro
5
(0)

Mcl-1 Lentiviral Activation Particles (h)

sc-400079-LAChGene ActivationPuro, Blast, Hygro
5
(0)

Mcl-1 Lentiviral Activation Particles (h2)

sc-400079-LAC-2hGene ActivationPuro, Blast, Hygro
5
(0)

Mcl-1 CRISPR Activation Plasmid (m)

sc-421589-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Mcl-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Mcl-1 siRNA (h)

sc-35877hGene SilencingN/A
79
(0)

Mcl-1 shRNA Plasmid (h)

sc-35877-SHhGene SilencingPuromycin
79
(0)

Mcl-1 shRNA (h) Lentiviral Particles

sc-35877-VhGene SilencingPuromycin
79
(0)

Mcl-1 siRNA (m)

sc-35878mGene SilencingN/A
6
(0)

Mcl-1 shRNA Plasmid (m)

sc-35878-SHmGene SilencingPuromycin
6
(0)

Mcl-1 shRNA (m) Lentiviral Particles

sc-35878-VmGene SilencingPuromycin
6
(0)

Mcl-1 siRNA (bovine)

sc-270511bovineGene SilencingN/A0
(0)

Mcl-1 shRNA Plasmid (bovine)

sc-270511-SHbovineGene SilencingPuromycin0
(0)

Mcl-1 shRNA (bovine) Lentiviral Particles

sc-270511-VbovineGene SilencingPuromycin0
(0)

Mcl-1L siRNA (h)

sc-43912hGene SilencingN/A
4
(0)

Mcl-1L shRNA Plasmid (h)

sc-43912-SHhGene SilencingPuromycin
4
(0)

Mcl-1L shRNA (h) Lentiviral Particles

sc-43912-VhGene SilencingPuromycin
4
(0)