Date published: 2026-4-28

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MATH-1 Activators

The chemical class of MATH-1 Activators includes a diverse array of compounds that can potentially stimulate or modulate the expression and activity of MATH-1, a transcription factor critical in neural development. This class encompasses agents like Retinoic Acid and Forskolin, which are involved in cellular differentiation and cAMP-mediated signaling, respectively, and could lead to the upregulation of MATH-1.

Compounds that enhance or mimic Sonic Hedgehog signaling, known for their role in neurogenesis, could also positively influence MATH-1 expression. Neuroprotective agents such as EGCG, Curcumin, and Resveratrol, with their broad effects on cellular signaling, are included for their potential to activate pathways leading to MATH-1 expression. Mood stabilizers like Lithium Chloride and HDAC inhibitors such as Sodium Butyrate and Valproic Acid, by altering gene expression and neuronal signaling, might also affect MATH-1. BDNF mimetics, essential nutrients like Zinc, and Omega-3 Fatty Acids, known for their importance in brain function and development, could potentially influence MATH-1 activity.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Involved in cellular differentiation, retinoic acid can influence gene expression, potentially leading to the upregulation of MATH-1 in neuronal cells.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Increases cAMP levels, which can modulate various signaling pathways and potentially enhance MATH-1 expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A component of green tea with neuroprotective properties, potentially influencing pathways that activate MATH-1.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Known for its anti-inflammatory and neuroprotective effects, curcumin can modulate various signaling pathways, potentially leading to the activation of MATH-1.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A polyphenol that influences various signaling pathways, potentially affecting MATH-1 expression.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Used in treating bipolar disorder, lithium can modulate signaling pathways involved in neurogenesis, potentially affecting MATH-1.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

A short-chain fatty acid acting as a histone deacetylase inhibitor, potentially influencing gene expression including MATH-1.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

An HDAC inhibitor that can affect gene expression, potentially upregulating MATH-1.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

An essential mineral important for brain function and development, which might influence MATH-1 activity.