MATH-1 Inhibitors
The chemical class of MATH-1 Inhibitors encompasses a variety of compounds that can suppress or modulate the expression and activity of MATH-1. This class includes agents such as Cyclopamine and Vismodegib, which inhibit the Hedgehog signaling pathway, a critical pathway in neural development that can influence MATH-1 expression. DAPT, a Gamma-secretase inhibitor, targets the Notch signaling pathway, another key player in neurogenesis, affecting MATH-1.
PI3K inhibitors like LY294002 and mTOR inhibitors such as Rapamycin can affect cell proliferation and growth pathways, possibly influencing MATH-1 activity. Mood stabilizers like Lithium Chloride and HDAC inhibitors such as Valproic Acid and Trichostatin A, by altering gene expression, could inhibit MATH-1. Compounds like Fluoxetine, Wnt pathway inhibitors, and Temozolomide, with their respective effects on neurotransmission, cell signaling, and DNA repair, are included for their ability to impact MATH-1 expression. Curcumin, with its broad spectrum of biological activities, might also play a role in modulating pathways related to MATH-1.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
An inhibitor of the Hedgehog signaling pathway, which can affect neurodevelopmental processes and potentially downregulate MATH-1. | ||||||
Vismodegib | 879085-55-9 | sc-396759 sc-396759A | 10 mg 25 mg | $80.00 $96.00 | 1 | |
A more specific Hedgehog pathway inhibitor that might also reduce the expression or activity of MATH-1. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
Inhibits Notch signaling, which is involved in neurogenesis and could indirectly affect MATH-1 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can affect various cellular signaling pathways, potentially including those associated with MATH-1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, which affects cell proliferation and growth pathways, potentially influencing MATH-1 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
While it can modulate several signaling pathways, in specific contexts, it might inhibit pathways leading to MATH-1 activation. | ||||||
Fluoxetine | 54910-89-3 | sc-279166 | 500 mg | $312.00 | 9 | |
A selective serotonin reuptake inhibitor (SSRI) that might influence brain development and neurogenesis pathways, potentially affecting MATH-1. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
An HDAC inhibitor known for its use in mood stabilization; it can alter gene expression and potentially inhibit MATH-1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor that changes gene expression patterns, potentially leading to the downregulation of MATH-1. | ||||||
Temozolomide | 85622-93-1 | sc-203292 sc-203292A | 25 mg 100 mg | $89.00 $250.00 | 32 | |
An alkylating agent used in cancer therapy, which can affect DNA repair and transcription processes, potentially influencing MATH-1 expression. | ||||||