Date published: 2026-10-20

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Macrocycles

Santa Cruz Biotechnology now offers a broad range of macrocycles for use in various applications. Macrocycles, which are large ring molecules consisting of twelve or more atoms, are critical in scientific research due to their unique structural properties and diverse functionalities. These compounds have found extensive use in supramolecular chemistry, where their ability to form host-guest complexes makes them valuable for studying molecular recognition and self-assembly processes. Macrocycles are instrumental in materials science, as their robust frameworks and ability to encapsulate ions or molecules enable the development of advanced materials, such as sensors, catalysts, and nanomaterials. In organic synthesis, macrocycles serve as scaffolds for the construction of complex molecular architectures, facilitating the creation of compounds with specific properties and functions. Environmental chemists utilize macrocycles to develop selective binding agents for pollutant detection and removal, contributing to advancements in environmental remediation technologies. Additionally, macrocycles are crucial in the study of biological systems, where they mimic natural macrocyclic structures like enzymes and nucleic acids, providing insights into biological mechanisms and interactions. Their versatility and capability to undergo functional modifications make macrocycles indispensable tools in research, allowing scientists to explore new chemical spaces and design innovative solutions across various scientific disciplines. View detailed information on our available macrocycles by clicking on the product name.

Items 81 to 90 of 288 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

β-Cembrenediol

57605-81-9sc-204635
10 mg
$316.00
(1)

β-Cembrenediol is a macrocyclic compound characterized by its unique ring structure, which promotes specific stereoelectronic interactions. This compound exhibits remarkable flexibility, allowing it to adopt various conformations that influence its reactivity. Its ability to engage in hydrogen bonding and π-π stacking interactions enhances its stability in solution. Additionally, β-Cembrenediol's distinct physical properties, such as its hydrophobicity, facilitate intriguing studies in supramolecular chemistry and molecular recognition.

Cyclosporin A-d4

59865-13-3 (unlabeled)sc-217987
sc-217987A
1 mg
10 mg
$643.00
$4994.00
(1)

Cyclosporin A-d4 is a macrocyclic compound distinguished by its intricate cyclic structure, which fosters unique intramolecular interactions. This compound exhibits a high degree of conformational adaptability, enabling it to participate in selective molecular recognition processes. Its hydrophobic regions and polar functionalities facilitate specific binding affinities, while its dynamic nature allows for diverse reaction pathways. The compound's distinct solubility characteristics further enhance its role in exploring complex chemical systems.

Antibiotic LL Z1640-4

66018-41-5sc-202056
sc-202056A
1 mg
5 mg
$211.00
$745.00
1
(1)

Antibiotic LL Z1640-4 is a macrocyclic compound characterized by its robust ring structure, which promotes unique intermolecular interactions. This compound exhibits remarkable stability and a propensity for forming non-covalent interactions, such as hydrogen bonds and van der Waals forces. Its conformational flexibility allows it to engage in diverse reaction kinetics, while its specific solubility profile aids in the exploration of intricate chemical environments, enhancing its reactivity and selectivity.

Dihydroavermectin B1b

70209-81-3sc-202139
sc-202139-CW
500 µg
500 µg
$307.00
$464.00
1
(1)

Dihydroavermectin B1b is a macrocyclic compound distinguished by its intricate ring architecture, which facilitates unique molecular interactions. This compound showcases a high degree of conformational adaptability, enabling it to participate in selective binding events. Its ability to form stable complexes through non-covalent interactions, such as π-π stacking and hydrophobic effects, enhances its reactivity in various chemical contexts, making it a subject of interest in complex reaction pathways.

Macbecin I

73341-72-7sc-204067
1 mg
$245.00
1
(1)

Macbecin I is a macrocyclic compound characterized by its unique cyclic structure, which promotes specific intramolecular interactions. This compound exhibits remarkable solubility properties, allowing it to engage in diverse reaction kinetics. Its ability to form dynamic host-guest complexes through hydrogen bonding and van der Waals forces enhances its reactivity profile. Additionally, Macbecin I's conformational flexibility contributes to its participation in intricate chemical pathways, making it a fascinating subject for study in supramolecular chemistry.

Concanamycin B

81552-33-2sc-221434
sc-221434A
100 µg
500 µg
$463.00
$1569.00
2
(0)

Concanamycin B is a macrocyclic compound distinguished by its intricate ring structure, which facilitates unique molecular interactions. This compound demonstrates exceptional stability and selectivity in binding to specific targets, driven by its conformational adaptability. Its ability to form robust non-covalent interactions, such as π-π stacking and hydrophobic effects, enhances its reactivity and influences its behavior in complex chemical environments, making it a compelling subject for exploration in molecular chemistry.

Bryostatin 2

87745-28-6sc-202086
sc-202086A
10 µg
25 µg
$270.00
$750.00
1
(0)

Bryostatin 2 is a macrocyclic compound characterized by its unique structural framework, which allows for versatile molecular interactions. Its cyclic nature promotes specific conformational arrangements, enabling selective binding to various substrates. The compound exhibits intriguing reaction kinetics, influenced by its ability to engage in dynamic hydrogen bonding and electrostatic interactions. These properties contribute to its distinctive behavior in diverse chemical systems, making it a fascinating subject for study in the realm of supramolecular chemistry.

Bafilomycin C1

88979-61-7sc-202073
1 mg
$612.00
(0)

Bafilomycin C1 is a macrocyclic compound distinguished by its ability to form stable complexes with metal ions, enhancing its role in modulating proton transport across membranes. Its unique ring structure facilitates specific interactions with cellular components, influencing ion gradients and pH regulation. The compound's dynamic conformational flexibility allows it to engage in transient interactions, leading to notable effects on cellular processes and providing insights into membrane dynamics and transport mechanisms.

Antibiotic TAN 420E

91700-93-5sc-202058
500 µg
$250.00
(0)

Antibiotic TAN 420E is a macrocyclic compound characterized by its intricate ring architecture, which enables selective binding to target biomolecules through non-covalent interactions. This structural design promotes unique conformational changes that influence reaction kinetics and enhance its ability to disrupt specific molecular pathways. Its hydrophobic regions facilitate interactions with lipid membranes, potentially altering membrane fluidity and impacting cellular signaling processes.

Calix[6]arene

96107-95-8sc-255010
250 mg
$272.00
(0)

Calix[6]arene is a versatile macrocycle known for its unique ability to form host-guest complexes through selective molecular recognition. Its cup-shaped structure allows for the encapsulation of cations and small organic molecules, leading to distinct supramolecular interactions. The compound exhibits dynamic conformational flexibility, which can influence its binding affinity and reaction kinetics. Additionally, its amphiphilic nature enhances solubility in various solvents, facilitating diverse chemical reactivity.