LYPD8 inhibitors are a class of compounds designed to specifically target and inhibit the function of the LYPD8 protein. LYPD8, encoded by the LYPD8 gene, is part of the Ly6/uPAR family, known for its role in modulating cell surface interactions. This protein is involved in the regulation of various cellular processes, particularly related to immune responses and cell signaling pathways. Inhibition of LYPD8 can alter the dynamics of these pathways, impacting how cells communicate and respond to environmental signals. LYPD8 inhibitors function by binding to the protein, preventing it from engaging in its normal interactions and thus modulating its activity without changing the overall expression of the protein itself.
LYPD8 inhibitors can vary significantly in their molecular structures, depending on how they interact with the protein. These inhibitors are typically small molecules designed to bind selectively to LYPD8's active or allosteric sites, disrupting its role in cellular signaling. Designing these inhibitors requires an in-depth understanding of the LYPD8 protein structure, as well as its specific binding sites, to achieve high specificity and effectiveness. Computational modeling and structural analysis are often employed to predict the most effective points of interaction, allowing for the creation of molecules that can precisely target LYPD8. By inhibiting LYPD8, researchers can study its involvement in complex biological processes, helping to elucidate its role in cellular regulation and interaction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits the mTOR pathway, affecting proteins involved in cell growth and autophagy, which can influence Tmem238. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A broad-spectrum kinase inhibitor, inhibiting kinases that phosphorylate or regulate Tmem238. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, affecting downstream signaling pathways that involve Tmem238. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAPK, impacting Tmem238 if regulated by or interacting with this kinase. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK1/2, which can affect Tmem238 if involved in the MAPK/ERK signaling pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, affecting Tmem238 if part of the JNK signaling pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor, can affect Tmem238 through downstream signaling pathways. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Src family kinase inhibitor, indirectly affecting the function of Tmem238. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Inhibits Protein Kinase C (PKC), impacting Tmem238 if associated with the PKC pathway. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Inhibits NF-kB activation, can impact Tmem238 if it's involved in the NF-kB signaling pathway. | ||||||